Is This Red-Hot New “Blood Stock” Any Bloody Good as an Investment?
by DrKSSMDPhD | June 18, 2014 5:12 pm
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Source URL: https://www.stockgumshoe.com/2014/06/microblog-is-this-red-hot-new-blood-stock-any-bloody-good-as-an-investment/
Dr. KSS, a little over a month ago, when I mentioned that by sitting on a toilet seat and moving my rump from side to side and back and forth to compress my hips in various ways it seemed to alleviate my hip-arthritis that at times was so severely painful I almost couldn’t walk without fear of falling. You indicated a possible benefit could be due squeezing the bursae, thereby dispersing some of the synovial fluid and improving joint lubrication.
So during the past month, while working with my computer often for several hours a day, I have been seated on a chair topped with a spare toilet seat, and I can report that the severe arthritis in both hips is greatly improved. Could this daily aggravation of the bursae be causing a greater natural production of more synovial fluid? Is the fluid in the bursae connected somehow with the fluid in the hip’s synovial cavity?
Robert, Speaking as a plumber, I think you should apply for FDA approval of your loo seat invention. But best if you post to the new thread coz your words of wisdom are being lost.
Re Mary D’you wanna, I had a whole field of the stuff outside my cave till they invented politicians !
Mr Paglee: yes, I think that is quite plausible as a mechanism for how it is helping. Obviously it is difficult to know for sure, given that I am not there examining your hips, seeing what evokes pain and seeing what motions relieve the pain. But simplistically, the signal for glands to make more mucus or secretions is when they have no backpressure from accumulated secretions, and so emptying the bursae may be inducing more synovial fluid synthesis. Synovial fluid is quite viscous…if you had a dab on your finger, you’d be able to draw out a thin bead of it between two fingers over considerable distance. Despite this it is very aqueous. If you try googling something like hip bursae diagram under Google Images, you will see several good drawings of where the bursae lie. There are perhaps 20 of them in and around the hip, though not all pertaining to the femoral head proper. Synovial fluid not only lubricates, but has very potent anti-inflammatory properties. But I think it is a plausible basis for the benefit you are getting, and I cannot see that such motions or movements would harm your hips in any way. I am glad it helps. Especially as we are in summer, good hydration is always advised as water is a principal component of synovial fluid. I might consider trying an oral hyaluronic acid supplement, if it seems from a reputable place, as that’s the main nonwater ingredient in the fluid and it is a complex molecule for the body to make. It is not “acidic” in the sense that it would harm the stomach.
Thanks, Alan and Dr.Kss. I was unaware there is a new thread — will have to look for it. As for my toilet seat RX, I was wondering if anyone else had tried this idea to get relief from hip-arthritis. It isn’t a cure, but seems to be maybe more natural and less costly than painkiller med’s or a radical hip-replacement as some of my friends have suggested. I’ll look into the possibility of a hyaluronic acid supplement .
But maybe a conventional toilet seat only works with small male hips like mine, that are slightly surrounded within the seat’s open oval. For some heavier people, a larger, specially built similar contraption could be needed. And I also have read that good hydration is advisable, so I increased mine and I believe that was beneficial, too. Thanks again for all your interesting, helpful comments.
Hi Dr KSS,
Your discussion about Tibetans and their magical high altitude blood properties was evoked when I read this Reuters article today about research on their genetics being traced to non-human ancestors. Enjoy if you haven’t seen it!
http://www.reuters.com/article/2014/07/02/us-science-tibetans-idUSKBN0F71WS20140702
Serendipity at large. When you click on the aforementioned link, you find this post on Reuters: How to fix an broken market in Antibiotics.
http://www.reuters.com/article/2014/07/06/us-health-antibiotics-insight-idUSKBN0FB0A220140706
With a telling comparison in price politics between Cubist an Gilead.
On the slideshow i found this remark: Two plates which were coated with an antibiotic-resistant bacteria called Klebsiella with a mutation called NDM 1 and then exposed to various antibiotics are seen at the Health Protection Agency in north London in this March 9, 2011 file photo. The clear areas in the right half of the left-hand plate show that the Klebsiella with NDM 1 was sensitive to the antibiotic tigecycline (manufactured by Pfizer under the trade name Tygacil). Does this means that there are now 2 antibiotics active on Klebsiella? Brilacidin and Tigecycline?
Ruud: Thanks for reading and posting. I would not infer too much from that picture. Most Klebisella isolates are sensitive to at least 3 common-use antibiotics.
While much is being made of bacteria resistance to antibiotics, I think that to some degree news media palavering about it is becoming long in the tooth. There actually is not that much evidence that there is a vast new crisis on our hands. There is a problem, yes, but not a NEW one……this war will go on forever.
In the war, there are 4 basic battlefronts:
(1) resistant Staph aureus….increasingly less of an issue, now that we have daptomycin, linezolid and tedizolid
(2) Acinetobacter baumanii
(3) Stenotrophomonas maltophilia
(4) carbapenem-resistant Enterobacter. Enterobacter means fecal bacteria, Carbapenems are agents like meropenem, imipenem and daropenem. Half of people who get CRE die from that as it is almost impossible to cure. This is why AKAO’s plazomicin is exciting.
CTIX’s brilacidin does in fact seem to be able to cure all 4 listed above. It has no known resistance. Much remains to be learned about it, but CTIX is a promising investment.
Thank you Dr KSS. I have an active interest on this klebsiella thing, because mine youngest has gotten infected with it, after multiple surgery for Crohns. Long story, horrible, frightening. Everything went wrong. After a Platzbauch they placed a mat. And on that mat the bacteria established itself. The doctors say it is a resistant version of Klebsiella and have no treat fot it. And that the situation now is reasonably calm and under control. He has a fistula, with little production. Now the doctors are monitoring the situation. Somewhere you made the remark that you saw no need for removal of the colon in case of Crohns. But I wonder how you came to that conclusion. The doctors had no other option. It was severly imflammated. Remicade useless. Powerless. And still are. Now I just try to do my 2 bit worth. And you have been very helpful, with your presentation of coming antibiotics.
Ruud: that is a horrible set of circumstances. If things came to platzbauch with fasziendeihszenz, then she has been extraordinarily ill and suffering.
My main point about Crohn’s disease and surgery is that surgery does not cure it, unlike the situation with UC. Nevertheless, some cases do come to requiring surgery, especially in cases of adhesions or tight stricturing that leads to obstruction. In these cases surgery can be quite mandatory, even though it does not cure the underlying disease process. And yes, cases that do not respond to infliximab are well-known. I tend to hope that these cases will respond to vedolizumab, a new monoclonal that blocks an integrin that allows white cells to home in on the gut (different from the TNF mechanism of Remicade). In many cases though Crohn’s patients come to surgery as a necessary way to save their lives, the surgery is only of mixed benefit long-term, in the splice points of the intestine tend to scar down and form sites of new obstructions. So, surgery is a last resort for Crohn’s.
Usually when people get pan-resistant Klebsiella such as she has, doctors try to use combinations of antibiotics to which is has intermediate sensitivity, or else to use the antibiotic colistin. Colistin is badly tolerated in most people however, and of course piling on the antibiotics just makes for more resistant forms of bacteria.
I forget where you are, but you might enquire about colistin if the Klebsiella is acting as a pathogen. I feel quite sorry for what is happening to her, as this is exquisite suffering. While combinations of antibiotics often have synergy for Gram-positives, that kind of effect is less clear, less predictable with Gram-negatives like Klebsiella. The antibiotic amikacin often helps but is toxic to ears and kidneys. A recent review article on this issue:
http://www.medscape.com/viewarticle/780065?pa=MNdzsFahA0zmnrjXtOrpi2vfae20aFfQDILjjOAnf0br%2B%2BcgDxgQOldCzx3FM1jppGF8k4rdXWuG7s9dnh0U9g%3D%3D
Alan: a B-grade wag in me wonders if the new smoking implements are called, in Blighty, “e-fags”? Or is that impolitic?
They are known as Fake fags. They look just like the old fags, but they dont do the business or have tantrums.
I once asked a new girlfriend if she smoked after sex. She said ‘it depends on how good you are.’
Yes, and every time someone describes to me a transcendent, epiphanical experience, I ask them if they felt the urge to light one up afterward.
I dont think she was referring to a cigarette……still perhaps neither are you. It can be difficult telling with KSS.