“Medicine’s $604 Billion ‘Memory Miracle'” Stock teased by Casey Extraordinary Technology

Identifying the Alzheimer's pick hinted at by Alex Daley

By Travis Johnson, Stock Gumshoe, February 24, 2014

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The phrase “Alzheimer’s Disease” sets off an almost pavlovian response among investors … we all know that Alzheimer’s is probably the least-understood major disease, and affects a spectacularly huge number of people, and even those who don’t get beyond fifth grade math can do the calculations: more than five million Americans have the disease, and that number continues to rise, people are living longer and already a third of senior citizens who leave this mortal coil have Alzheimer’s or some other form of dementia at the end of their lives. That’s a LOT of potential patients.

And they have almost nowhere to turn — there are a few approved drugs that help some patients with some of the symptoms of Alzheimer’s, particularly memory loss, but they don’t do anything to cure, prevent or reverse the disease. That’s the golden ticket for pharmaceutical companies, but the search for cures has also burned many big pharma companies and sent quite a few little biotechs into death spirals — there’s still plenty of debate about exactly what causes Alzheimer’s, the trials are expensive, and many companies have spent millions of dollars (or hundreds of millions) only to find out that their compound had dangerous side effects, or was ineffective.

Some of the big pharma companies have effectively given up on the disease for now, but there are still a half dozen heavyweights pushing through clinical trials — mostly for BACE inhibitors, which are designed to stop the formation of amyloid plaque (the most likely cause of Alzheimer’s, according to many but certainly not all scientists). Other BACE inhibitors have failed, but hope springs eternal — and there are also, as Doc Gumshoe noted in a brief update a few months ago, more than 1,000 clinical trails going on in Alzheimer’s disease (that includes treatment protocols and devices as well as drugs, but there are a lot of drugs).

Which is a long way of saying that yes, Alzheimer’s is probably the largest underserved market in medicine. And has been for longer than Stock Gumshoe has been around (that’s seven years now). Every time any halfway appealing Alzheimer’s drug enters clinical trials, investors jump on the story … especially when it’s a smaller company (“Pure play” biotechs are always sexier because they offer more ridiculous upside — Merck (MRK), for example, has a Phase III drug in trials now that is generating some hope … but even an anticipated market of perhaps $5-10 billion for their drug by some analysts doesn’t have people lusting after the stock, given Merck’s $160 billion market cap and $44 billion in sales last year).

And the stock being teased as an Alzheimer’s pick today by Alex Daley at Casey Extraordinary Technology is, indeed, a relatively small company with an Alzheimer’s drug in clinical trials. And no, it’s not the tiny one that was teased several times in 2010 and 2011 (that was Anavex Life Sciences, AVXL, which was around $3 when first teased and is now down around 25 cents… their lead drug is now “Anavex Plus” and is a cocktail of their lead compound, Anavex 2-73, mixed with Pfizer’s Aricept (the current far-and-away leader in Alzheimer’s symptom-attacking drugs).

So what is it? Here’s the intro which provides the first couple of clues:

“We’ve just uncovered an amazing story about one man’s recovery from one of the world’s most dreaded… and expensive… diseases. His groundbreaking drug treatment could soon become widely available and dominate a $604 billion medical market.

“And in March 2014, the entire world will find out why. The payoff to you could be astronomical… with triple-digit gains possible in one day….

“It’s no wonder the National Institute on Aging calls this disease a ‘looming health epidemic.’

“And the few drugs on the market that treat this disease—approved more than a decade ago—only target the symptoms of this degenerative brain disease and not the underlying cause.

“Yet, even with their limited effectiveness, their combined sales last year topped $6 billion, according to BCC Research.

“Analysts estimate that a treatment that targets the cause of the disease itself could generate sales of $20 billion or more.

“As you probably know by now, the disease is Alzheimer’s.

“ABC News recently reported that it’s ‘…the only one of the top 10 causes of death in America that cannot be prevented, cured or even slowed down once it begins.’

“But that’s about to change…

“Because in March 2014, one little-known biotech will release its biggest clinical results yet on a groundbreaking new Alzheimer’s treatment that could forever change the course of this terrifying disease.

“It’s the first treatment ever to target the cause of Alzheimer’s… rather than just relieve the symptoms.”

And we get a glowing endorsement from one of the patients who was apparently in the clinical trial:

One Red Capsule Gives Walter His Memory… And Life… Back….

“Once a day he was given a red capsule—developed by this fledgling biotech—and within the first month, his memory started to return.

“He started to remember little things like where his favorite cup was.

“According to the investigator who’s overseeing the clinical trial, Walter’s improvement was simply ‘incredible.’

“And over the next 14 months, he became a poster child for success in clinical trials.

“Walter and his wife were elated. Walter called the breakthrough treatment ‘a godsend,’ and his wife called it ‘amazing.'”

So there we have it — the promise from Alex Daley is that he has identified a stock which will report some kind of clinical data next month, and has shown progress in at least some patients, and it’s a smallish company which would presumably feel a strong impact from whatever the results of that clinical trial might be. Big potential market, large near-term catalyst — the kind of stuff that gets traders very excited … especially when you happen to be in the midst of a biotech bull market, as we are now (or a biotech bubble, if you want to be more cynical).

And just to make sure we dot the i’s and cross the t’s, let’s see what other details Daley provides for this secret pick:

“You Could Make Life-Changing Gains From This Breakthrough Alzheimer’s Discovery

“Deutsche Bank estimates the market for this company’s breakthrough Alzheimer’s treatment could be worth $20 billion annually.

“So we’re looking at a tiny biotech—$485 million market cap in early February—that’s set to dominate a $20 billion drug market with a one-of-a-kind, patented breakthrough treatment.

“Even if it only captured a small 20% of this enormous potential ($4 billion), this booming biotech’s possible projected value would be enormous. If the company traded at just 1x its annual sales—well below the typical industry multiples of 2.5x to more than 5x—its shares would trade at about $98.

“As I write you, the stock’s price is hovering around $11.28 per share; that’s a massive 769% potential gain from this tiny biotech that’s extremely undervalued at its current price.”

So who is it? Well, we did haul out the Mighty, Mighty Thinkolator on this one just to be certain of our match … but this is 99% sure to be Prana Biotechnology (PRAN), the current market darling small cap stock in Alzheimer’s. The company has been mentioned in reader comments a few times over the past year, including from some folks who likely enjoyed nice returns as it climbed dramatically last year (it was around $2 a year ago, climbed to $12 last month, and is now back down around $9).

Their basic science is being used to attack both Huntington’s Disease (the clinical trial is called the Reach2HD trial) and Alzheimer’s Disease (the IMAGINE trial). The Huntington’s results last month were apparently good (though there’s some debate), and investors are very eagerly awaiting the IMAGINE results that are expected to come out sometime in March. If I begin to talk about the science, I’ll instantly start to sound uninformed … so I’ll avoid that entirely and just say that this is not the same path that the BACE inhibitor drugs (like Merck’s, etc.) are treading, they’re instead essentially targeting metals in the brain as a cause of neurological disorders.

We have been hosting an incredibly long discussion thread on other biotech stocks that grew organically out of a prior teaser article, and in that thread Prana came up along with several other “hot topic” stocks in biotech — so you can see the comments of some of our more knowledgeable readers there, including from biocqr here, karmaswimswami here (Karma was responding to Frenchy’s question about Prana, here). I imagine all those folks probably know more about the stock than I do.

For outside thoughts on Prana, there’s been a huge surge of interest at SeekingAlpha with both strongly negative and positive opinions — which tends to happen with most biotechs or rapid growers. This piece and this piece recently caught my eye as being pretty well thought-out, though I don’t know if they’ll end up being correct. On the flip side, Adam Feurstein over at TheStreet has been generating piles of hate mail for himself by writing a series of negative or cautionary articles about Prana over the last week (one example here).

So yes, if Prana can cure Alzheimer’s they’ll become a multi-billion-dollar company. But there’s plenty of skepticism out there about whether that can happen or not, and I don’t know whether the FDA’s new guidelines that they’ll accept limited proof of efficacy will have any impact on the multi-year safety studies that would likely be required before approval… but there will be news next month that provides at least a little more ammunition for either the bulls or the bears (or maybe, given the Huntington’s results, both). I’m sure there are at least dozens of folks here who know far more about this stock than I do, so feel free to chime in and share your thoughts with a comment below.


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69 Comments on "“Medicine’s $604 Billion ‘Memory Miracle'” Stock teased by Casey Extraordinary Technology"

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Dr. KSS MD PhD
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karmaswimswami
February 24, 2014 3:20 pm

In the eighties it was aluminum. Yep, Alzheimer’s was from all that Diet Coke drunk from cans. A few years later, copper. And then iron.

Before all of this falderal is over, science will have fingered titanium, tin and antimony. Arsenic, molybdenum and vanadium.

Metals hang around as prosthetic groups in damaged proteins when tissues get injured. They are rarely the cause of the injury. If you break a leg, you get bruises. But you cannot help the leg heal by using an agent that makes the bruises go away.

Rosenmeyer
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Rosenmeyer
February 24, 2014 3:24 pm

net net PRAN is garbage imo-one of only 2 bios I am currently short-TNXP the other one

Dr. KSS MD PhD
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karmaswimswami
February 24, 2014 3:34 pm

Miller: TNXP is complete and utter garbage. Good on you for shorting it. I have rarely seen more audacious merchants of hubristical nonsense than Tonix. They take investors for fools and will themselves be had. Cyclobenzaprine is a rotten drug and cannot be reinvented for anything useful for anybody. That they think they will reformulate it, charge 10 times more, and succeed is just delusional.

Elliot Sedlecky
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Elliot Sedlecky
February 25, 2014 8:34 am

Thanks for the thoughts on TNXP. I am long and up about 75% since buying in. Due to your thoughts, I am going to sell half today. With the other half, I would like to ride the hype as I believe it is likely not over. Any thoughts on how I might best place a stop? Currently thinking I’ll place a trailing stop of 14%.

bronx54
Member
0
bronx54
March 1, 2014 3:39 pm

How do I see your early post..I am new to GS….Wanted to read your early post
on Bio techs. I am 79 and a little slow getting on to this.
Thank you

tompaol
Member
56
tompaol
February 24, 2014 3:49 pm

Wall Street Daily was touting this last week as well. Its up $1.00 today. 18% The question is is it worth the risk?

modernrock
Irregular
232
February 24, 2014 6:54 pm

can’t find it on their website and don’t recall seeing it in any of their pieces. must have missed it. Seeking Alpha had an article out Friday with an $800 target, yes $800 on approval. Most likely the big gap and run, not this tease.

tompaol
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tompaol
February 24, 2014 3:49 pm

Sorry that is 12.83 % not 18%

Goodwin
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Goodwin
February 24, 2014 4:19 pm

I’ve just read the alternative medicine’s HSI Health Sciences Institute on Alz, Canc, Diab, et al which slams the pharmacies and the FDA for promoting their “poisons ” when there are far better proven alternatives without the dreaded side affects available. Does anyone out there have any experience of the HSI recommendations ?

Dr. KSS MD PhD
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karmaswimswami
February 24, 2014 5:55 pm

I recommend avoiding HSI. Pseudoscience.

dcohn
Irregular
159
February 24, 2014 6:01 pm

That is the issue. There are crooks on all sides of the problem making the solution hard to find. I am not disagreeing with your comment about HSI but all these people that did studies on dairy products, soy products and wheat being literally poison for your body are true. Getting the public to accept it when Marijuana is illegal but ALLEVE is over the counter is insane.

jer_vic
Irregular
338
jer_vic
February 25, 2014 1:10 pm

“By definition”, I begin
“Alternative Medicine”, I continue
“Has either not been proved to work,
Or been proved not to work.
You know what they call alternative medicine
That’s been proved to work?
Medicine.”
—Tim Minchin

lookinforvalue
Member
1
lookinforvalue
February 24, 2014 4:55 pm
did no read HSI data however Dr. Newport from Tampa Fl. has written a book “what if there was a cure for Alzheimer’s and no one knew?” Calls Alz diabetes of the brain because the brain thrives on cholesterol and statin drugs for one reduce Ch. Also lo fat diet. Switch to Coconut Oil for cooking and take a tlbs a day out of the jar. Visit her website (google it) for her story of her husband who had no life and now he does. Coconut oil is a fatty acid found in mothers milk and coconuts.
Fred Di Francesco
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Fred Di Francesco
March 3, 2014 4:39 am
The doctor to whom you refer is Dr. Mary Newport; I’ve read her amazing story, as part of my own look into Coconut Oil. There are lots of links to her; here’s one: http://tv.greenmedinfo.com/man-dramatically-reverses-alzheimers-symptoms-with-coconut-oil/ My doctor wanted to put me on statins; I told him: NO WAY, started researching alternative ways to deal with cholesterol, and ran into Coconut Oil. I’ve read several studies done on the populations that eat a diet rich in Coconut Oil, primarily the Polynesians. They find no evidence of obesity, heart or vascular complications linked to Coconut Oil. The misunderstanding comes from the fact that… Read more »
Lane Simonian
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Lane Simonian
February 24, 2014 5:37 pm
The results of Prana’s phase two clinical trial for Huntington’s disease was somewhat lackluster. At a high dose, Prana’s PBT2 produced a slight, but significant improvement in executive function in early stage Huntington’s patient. It did not produce any other improvements. PBT2 may accomplish something similar for early stage Alzheimer’s patients (we will know more when the company releases its results in March). The primary cause of Alzheimer’s disease is a toxic oxidant called peroxynitrite. Peroxynitrites inhibit the synthesis and release of neurotransmitters involved in short-term memory, sleep, mood, alertness, and social recognition, reduce the flow of blood and the… Read more »
Dr. KSS MD PhD
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karmaswimswami
February 24, 2014 6:10 pm
Lane: Thanks for posting, but I cannot agree with all of that. There is no evidence of omega-3 benefit in Alzheimer RCTs. There is no consensus whatsoever on what a Mediterranean diet is. There is no evidence that polyphenols benefit Alzheimer patients. The peroxynitrite notion is a hypothesis from the late 90’s that literally appeared in “Medical Hypotheses,” a journal, and there is little to support any idea that this had advanced since the 90’s with the exception of autopsy studies. If this hypothesis were correct, Wilson disease patients would all get Alzheimer disease prematurely and they never do. There… Read more »
Lane Simonian
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Lane Simonian
February 24, 2014 11:22 pm
To respond thoroughly to all of your points would take a book. I will try to be as efficient as possible. Omega-3 fatty acids and polyphenols inhibit the production of peroxynitrites and this is likely why they may reduce the risk for Alzheimer’s disease. Neurobiol Aging. 2005 Dec;26 Suppl 1:133-6. Epub 2005 Nov 2. Prevention of Alzheimer’s disease: Omega-3 fatty acid and phenolic anti-oxidant interventions. Cole GM1, Lim GP, Yang F, Teter B, Begum A, Ma Q, Harris-White ME, Frautschy SA. Safety concerns with chronic NSAIDs led to a screen of alternative NSAIDs and identification of the phenolic anti-inflammatory/anti-oxidant compound… Read more »
Nikki
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Nikki
February 25, 2014 1:29 pm

Lane, thank you so much for this great information – from both an investor’s perspective but especially for those of us interested in non-pharmaceutical answers to devastating diseases such as this. Do you know if the general public has access to the substances you mention? That form of ginseng, especially? Again, thanks for taking the time to provide such excellent explanations and info.

Lane Simonian
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Lane Simonian
February 25, 2014 2:15 pm
There is a supplier for sun ginseng (heat-processed ginseng) operating out of Los Angeles, California (the exporter is Ginseng Science; the importer is Sun Sam, incorporated). The cost for a month supply (based on the dose used in the clinical trial) is about $700 a month. Sun ginseng is produced via a patented process of alternating between steam heating and drying of Panax ginseng. At a high dose, red ginseng which is produced by steaming led to some improvements in cognition in Alzheimer’s patients which were maintained over a nearly two year period, but the results with sun ginseng were… Read more »
claresa
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claresa
March 2, 2014 11:19 am

lane, wow, thank you so much ! i use the paleo diet and i’ts keeping me away from the doorstep of lots of troublesome stuff like: diabetes ! i first found out how important this stuff was and options of prevention, around five years ago, when seeking solutions to problems that led to the gaps diet ! these dietary solutions have been nothing less than life saving !

pathman1
Irregular
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pathman1
February 24, 2014 6:24 pm

Lane: Excellent piece! Thanks for taking the time to put this together.

Lane Simonian
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Lane Simonian
February 24, 2014 11:24 pm

Thank you very much. I once was wisely told that extraordinary claims require extraordinary evidence. I look almost every day for the best evidence available.

James Teck
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March 2, 2014 5:05 pm

Could you comment on the potential of peroxynitrite scavengers to treat Parkinson’s?

Lane Simonian
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Lane Simonian
March 2, 2014 9:44 pm

The footprints of peroxynitrites are all over Parkinson’s disease as well. Some studies suggest peroxynitrite scavengers such as minocycline and uric acid can be of some benefit in the treatment of Parkinson’s. There are probably better alternatives in the forms of various natural antioxidants, but the human studies don’t seem to be there yet. Here is a good review article, however.

Review
Recent Advances on the Neuroprotective Potential of
Antioxidants in Experimental Models of Parkinson’s Disease
Sushruta Koppula, Hemant Kumar, Sandeep Vasant More, Byung Wook Kim, In Su Kim
and Dong Kug Choi *

dcohn
Irregular
159
February 24, 2014 5:55 pm
I am the furthest thing from a knowledgeable western medicine person but with all the resent news regarding the very clear and proven dangers of eating WHEAT and evidence that has shown that many of the food preparations we eat are the direct cause for these illnesses. Knowing and seeing this first hand I simply do not believe these are true cures YET they may do enough to make billions. If Rockefeller and Carnegie did not create Allopathic medicine the US would be a much different place where Homeopaths and Osteopaths and Chiropractors would be the medical profession and we… Read more »
Chris
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Chris
February 24, 2014 5:56 pm

Hopefully something work,s who gives a crap how much money is made. That`s Evil!!

dcohn
Irregular
159
February 24, 2014 5:58 pm

Sorry but here is a link that shows info specific to Alzheimer using all Natural methods. Such as not eating poisons.
http://articles.mercola.com/sites/articles/archive/2013/09/29/dr-perlmutter-gluten.aspx

Dr. KSS MD PhD
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karmaswimswami
February 24, 2014 6:12 pm

Anything by Mercola should be held between thumb and forefinger at arm’s length. And use your other hand to pinch your nose shut. One of the most execrable scoundrels and snake oil merchants ever to visit himself on naive people.

dcohn
Irregular
159
February 24, 2014 8:33 pm
I used to believe that as well but after seeing all the good he has to say and do I have since changed my opinion. I will not attempt to sway anyone elses opinion and apologize if I took the comments off track in anyway. the medical establishment kills 783,936 people in the United States every year http://www.naturalnews.com/036599_gun_control_prescription_drugs_deaths.html##ixzz2uIEsMw5i I would like to add that if Mercola is a snake oil salesman what is a plastic surgeon? A respected part of society? How on earth did it turn out like that I simply do not understand. More people die from prescription… Read more »
Nikki
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Nikki
February 25, 2014 1:34 pm

Hear, hear!! Totally agree with you, Douglas.

Anon. viewer of www,stopthecrime.net
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Anon. viewer of www,stopthecrime.net
February 25, 2014 9:52 pm
In total agreement. Anyone seeking to live in peace and harmony with less stress in accordance with the laws of nature should seek to invest in areas that do much more benefit than harm. In investments I try to follow the biblical injunction not to harm the earth, the seas or trees. I prefer natural supplements and herbs in resonance with my own personal energetic system to synthetic drugs whenever possible. Less karmic backlash helps me sleep better. With the increase in toxins in the environment and our food and water, depletion of oxygen levels in our air and nutrients… Read more »
bronx54
Member
0
bronx54
March 1, 2014 3:43 pm

How do you get to read your eariler post. I am new to GS and
79 and a little slow in getting on to this.
I would love to read your comments on other Bio techs.
and what you like and don’t like.

Thank you

dcohn
Irregular
159
February 24, 2014 6:06 pm

And if you all do not want me to go away here is one link that may enlighten your further regarding other diseases created by our insane policies IE what cane be used on our food when growing creates poison. See John’s great article below.

http://jonrappoport.wordpress.com/2014/02/24/email-from-author-of-study-on-roundupgluten-intolerance/

Sam
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Sam
February 24, 2014 6:50 pm

karmaswimswami,

What about SGMO? Their Phase-2 data is coming in 2015.

Also what about a penny stock from Canada AVXL?

Dr. KSS MD PhD
Guest
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karmaswimswami
February 24, 2014 6:57 pm

Sam: Let me look into Anavex. The sigma receptor stuff is newish science. They are not well capitalized and still almost all pre-clinical. With Sangamo are you referring to the Zn-finger program for HIV?

Sam
Guest
0
Sam
February 24, 2014 8:14 pm

Thanks a lot Dr. karmaswimswami.

I am referring to their “Alzheimer’s Disease – CERE-110.

Looking forward to Your Response.

abxyz0101
Member
27
abxyz0101
February 24, 2014 6:53 pm

I am impressed by fact that there was a 95% retention rate in study and only one report of adverse reaction which was worsening of one patient after discontinuation of the drug. There are no sure fire bets in stock market for a commoner like me. I have taken a small speculative position. Wall street is a casino believe it or not. Rising market creates armies of geniuses; falling market of fools you wouldn’t know as they become invisible.

ectopicbrain
Irregular
37
ectopicbrain
February 24, 2014 6:58 pm

I hate it that I have to post a banal comment in order to get notified of new postings!

Meg in Minneapolis
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0
February 24, 2014 7:46 pm
My mother had Alzheimer’s, so I am motivated to try to avoid it. To date, I am aware of no efficacious drug. So I look to “alternative medicine.” Studies conducted by the University of Chicago are compelling. Their studies began in the 1930’s, when they sent graduate students to two towns in Texas. One town has a very high crime rate. Students soon recognized that this town also has a high rate of Alzheimer’s Disease, Parkinson’s Disease, ALS, rheumatoid arthritis, obesity, and anorexia. All of these conditions are rare in the town right next to it. Students worked for decades… Read more »
dcohn
Irregular
159
February 24, 2014 8:11 pm

I fully believe that the quality of the water we drink and bathe in has a long lasting effect on our health. There are so many studies done on water and how crucial it is to our health. There are some things you cannot just jam into a bottle made of plastic and expect it to be anything like artesian or glacial water even if it comes from such areas.

abxyz0101
Member
27
abxyz0101
February 24, 2014 8:37 pm

Lithium carbonate is used to treat Bipolar Disorder, average dose being 300 mg three times a day with a target blood level of 0.6 to 1.2 mEq/L. Therapeutic window is small; it can be quite toxic when blood levels rise above 1.2.
I believe when taken as nutritional supplement, the dosage can be as small as 10 to 20 mg. I would like to know from Meg what was the dose you used. Apparently you used amino acid chelate of lithium, so the dosage may not be directly comparable with carbonate form.

Meg in Minneapolis
Guest
0
February 24, 2014 10:54 pm
Sumanial – I buy my Lithium Aspartate from Swanson Vitamins…100 caps for $4.99, each cap providing 5 mg. From things that I have read, Lithium Orotate, 5 mg. provides the same benefits. I add that there is also an association between Alzheimer’s Disease and low thyroid function. For prevention…and for improved quality of life…I think that it is wise to add an iodine supplement. Noteworthy: Five doctors tested all their patients, learning that 94.8% were deficient in iodine. I like Iodoral, that provides both Iodine and Iodide. Vitamin A (another common deficiency) also improves thyroid function. For anyone who notices… Read more »
YIN TSE
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YIN TSE
February 24, 2014 8:39 pm

All the BS, all the BS….., all the BS….
How do they relate to PRAN, the stock? really.

abxyz0101
Member
27
abxyz0101
February 24, 2014 9:05 pm

PRAN will be worthless if off shelf alternative natural supplements (Lithium?) will do the trick of helping/improving AD/Huntington’s. Even a non rocket scientist will understand.

lily
Member
0
lily
February 24, 2014 11:04 pm

Ditto what Louis said. Is there a way to follow a thread without posting?

abxyz0101
Member
27
abxyz0101
February 25, 2014 6:39 pm

Tangent is fine.
Benitec (BNIKF in OTC) closed today at $1.94, up 12 cents on a 300,000 + volume.
It had private placement of 35 million units yesterday at Australian $1.07 each. The purchasers/financiers are sitting on 90% cool gain in one day, but it won’t last. As they try to cash in the gain price will come down. I will nibble around $1.20 still leaving them 20% gain for their troubles.

What does BNIKF has to do with PRAN?
Both are equally pretty for a horny.

yogiman
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yogiman
February 26, 2014 11:11 pm

You can bookmark this page, then refresh ( Control F5) each time before using. Claire, you should also check out this thread for GS. http://www.stockgumshoe.com/reviews/biotech-supertrader/this-tiny-unknown-biotech-is-about-to-unleash-its-holy-grail-drug/#comments

pmd3nka
Irregular
6
pmd3nka
February 25, 2014 3:25 am

There is another Australian stock that has taken off, far more than Prana. It is Benitec (BLT on ASX), which is testing a Hep C `cure’. Any comments?

Sorry to be off on a tangent.

Phil

yogiman
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yogiman
February 26, 2014 11:13 pm

Phil, see above link.

Dr. KSS MD PhD
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karmaswimswami
February 25, 2014 7:23 am

to Phil Diamond: yes we know all about Benitec. I have been touting it here since last year. Please go to the other thread in Gumshoe.

Buygold
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0
Buygold
February 25, 2014 11:24 am

I am new to the biotech area and my father-in-law that I am very close to is suffering with Alzheimers. Are the statements that Casey Research makes about Walter Lewis and others gaining their memory back after taking this drug really true? Are these facts somewhere besides in Casey’s ad?

Frenchy
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Frenchy
February 25, 2014 12:16 pm

Hi everyone, simply making my initial entry:)

dave
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dave
February 25, 2014 12:33 pm

I believe a much safer betfor growth is in lo term care l. These deseases are not finding cure. Bsby boomerd are retiring and nursing homes are filling up as fast as they csn be built. In fact during the housing frrrze on lending a few years back these places where the only things be built. At least herein my neck of the woods.

Carbon Bigfoot
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Carbon Bigfoot
February 25, 2014 2:42 pm

I read the Phase II results and they don’t provide the success assigned to the hype.
Intermune on the other hand had a real push to day. Whether the 50-75K patient base is worth the valuation only time will tell.

Dr. KSS MD PhD
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karmaswimswami
February 25, 2014 4:39 pm

So, ginseng and special foods are special for Alzheimer’s because they are anti-oxidants? I don’t think so. Those foods are tiddlywinks in reductive potential. Once again, natural/alternative belief system has it in for facts and data and trials. For drugs because they are made in a “laboratory” and not natural. If the peroxynitrite theory had any credibility at all, arginine would totally ruin cognition in Alzheimer dementia by acting as a donor for NOS, and yet it seems to help.

Lane Simonian
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Lane Simonian
February 25, 2014 7:06 pm
People get confused because endothelial nitric oxide in itself is generally helpful (improves bloodflow, for instance). However, the oxidation of BH4 (a cofactor for nitric oxide production) by peroxynitrites results in the “uncoupling” of endothelial nitric oxide synthase resulting in the production of superoxide anions instead of endothelial nitric oxide. Nitric oxide (NO·) is an important protective molecule in the vasculature, and endothelial NO· synthase (eNOS) is responsible for most of the vascular NO· produced. A functional eNOS oxidizes its substrate L-arginine to L-citrulline and NO·. This normal function of eNOS requires dimerization of the enzyme, the presence of the… Read more »
kurtwalter
Irregular
0
kurtwalter
February 26, 2014 12:04 pm

Up 24% today,

Curious
Guest
0
Curious
February 26, 2014 2:46 pm

So, should we sell? Or keep this stock?

abxyz0101
Member
27
abxyz0101
February 26, 2014 6:58 pm

Proof is in the pudding; up 25% in 2 days. Will sell in May and go away.

Jac Guns
Guest
0
Jac Guns
March 2, 2014 7:07 am

There was a big study in the Netherlands.
Conclusion, arteriosclerosis is the cause for dementia.
Science journalist Kirsten Emous, wrote a book about it.
De doolhof van tante Anna.(The labirinth(maze) of aunt Anna)
I did not read it yet. Maybe someone can translate it.

arch1
Irregular
5253
March 2, 2014 9:56 am
How do you argue with a belief system? If that’s how you wish to invest suit yourself. A mathematical case could be made that the ingestion of “nutriceuticals” [vitamins,supplements] causes alzheimers since the rate of use vs. disease increase is similar. Similar to truism “everyone who habitually ingests Dihydrogen oxide dies.” Personal view is that DNA deterioration is the main cause; we are all copies of copies of copies etc. & alzheimers does ‘run in families’. Also general aging of population means increase of geriatric problems. On the other hand; hucksters who sold snake oil did make money.
jer_vic
Irregular
338
jer_vic
March 3, 2014 11:22 am

“Science adjusts its views based on what’s observed. Faith is the denial of observation, so that belief can be preserved.”
Tim Minchin (again)

Solyom
Guest
0
Solyom
March 2, 2014 1:41 pm

For those looking for an alternative medicine for alzheimer’s disease I suggest you study this link carefully.
http://www.neuroanatomy.wisc.edu/selflearn/Nuns&alzheimers.htm

1] Nuns don’t retire.
2] Few drink excessively
3] But those nuns that were educated well by their parents did not manifest the disease during their life time. If you want your kids to not manifest this illness educate them well

For yourself learn a new foreign language. Take classes at local community college.

By the way I am a neurologist that runs a free medical clinic.

http://www.neuroanatomy.wisc.edu/selflearn/Nuns&alzheimers.htm

snsm
Irregular
0
snsm
March 2, 2014 2:17 pm

What about Mercury? I have a mouthful of amalgam filled teeth which would cost a fortune to replace.

Buygold
Guest
0
Buygold
March 2, 2014 4:15 pm
It is very interesting that Casey mentioned March test results. Before Gumshoe did this article, I had researched what stock Casey could be talking about. I came up with two stocks in Alzheimer’s drug development that have results coming out in March, Prana and Anavex Life Sciences AVXL. So I bought both. Since I bought them and as of Friday’s close, PRAN is up 24% and AVXL is up 18%. AVXL was actually up over 50% earlier in the week. Does anyone know about AVXL and whether some analyst promoted them this week? Or perhaps there were others like me… Read more »
baygreen
Member
32
March 3, 2014 12:34 am
Is it what you eat or what you swallow, could it be how long you sleep or are awake, what is digested and what stays, everything has a piece of life. But a proven smile that is real and shared with others not if but when they meaning whoever slows down and cures what we will all naturally have unless something unfortunate happens. Let them work on the cure but the cure is living with what you are the best way you can. That I would invest in but there is no that without you. Make a difference and you… Read more »
green
Guest
0
green
March 14, 2014 6:30 pm

perhaps imagine the regen therapeutics, low light, spotlight a few, that’s right.
but the great discoveries soon!

bigriodog
Member
1
bigriodog
May 20, 2014 8:47 pm

Another Great Call by GUMSHOE….You could have made a fortune. The stock was $10 a share in February on May 20th its $1.58. Like I said, you could have made millions on this stock – BY SHORTING IT….LOL

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