“Biotech Scientists Discover ‘Magic’ Keys to Immortality” (“Dr. Allen’s … RNA Interference Revolution: Your Ticket to Centuries of Health and Wealth”)

The Oxford Club says that "The First Person to Live to Age 1,000 Has Already Been Born" and pitches this stock as the "Death of Social Security"

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[Ed note: This article was originally published in June, 2013 when the shares of the stock teased, Alnylam (ALNY) were around $30 and the Oxford Club was saying that the first person to live to 1,000 is already alive … now they’re touting it as the holder of the “Magic” Keys to Immortality, but the tease and the details (and the stock) are still the same. The latest pitch is based partly on upcoming catalysts, particularly the “winding down” of Phase 2 studies on their lead drug and the likelihood that they will soon get approval to start Phase 3 studies for this drug that has an FDA “orphan” designation, which they think will rocket the stock higher.

What follows has not been updated, edited or revised, but ALNY is now a $11 billion company with a share price of roughly $110, it has had its ups and downs after being teased two years ago, but it has been generally very strong and we last re-published this piece about a year ago when the stock was at less than half this price. I don’t know a lot about the company or the science behind it, and didn’t know much about it then either (sometimes I’ve got an opinion, sometimes I can just get you the stock name and ticker and let you get started on your own), so I’m republishing this instead of re-writing it — that will let us stay connected to the original stream of comments. If you want to see some of the more recent chatter on this, you can also check the article we wrote when Michael Robinson was using a similar “How to Live Forever” shtick in teasing this same company, about a month ago, for his Nova-X Report.

I hope you find the following helpful, but it at least answers the question so many have asked: “what’s Oxford Club’s ‘Magic Keys to Immortality’ stock?”]

—-following was published June 29, 2013 and has not been edited or updated—

“Just one company stands to make the lion’s share from this radical life extension phenomenon…

“It’s locked down nearly every patent behind this technology.

“The founder of this company, a Nobel Prize-winning scientist, is the same man who founded one of the most storied biotech companies ever.

“His first biotech outfit saw its stock go from $3.08 a share to over $240 a share. That’s when his company developed and released a treatment for a debilitating – and often deadly disease.”

I can see why so many folks have been asking about this latest pitch from the Oxford Club — not only do you get that kind of exciting story, but you also get the coincidence that the folks who buy investment newsletters tend to mostly be in their 60s and 70s and quite interested in health and rejuvenation and life extension, and the ad came in under the headline that …

The First Person to Live to Age 1,000 Has Already Been Born…

Presumably that’s going to be one of the people who are a few months old now, and you also have to see a real exponential hockey-stick chart of life expectancy to get to 1,000 years old — along, of course, with a complete change to the structure of human life on earth — but the more realistic-sounding projections, based on some big breakthroughs like the one being teased here, are that it’s possible for adults alive now to reach 150 years of age, and that the longer you live the more science will catch up with you and push that envelope further. Of course, you won’t be able to retire at 65 if you’re looking at making those monthly condo payments for another 80 years after that, but presumably you’ll be so strong and vibrant that you’ll be working as a longshoreman for a little fun and pocket change in your spare time.

But anyway, this Oxford Club pitch is that there’s a spectacular biotech company that’s got RNA technology patents locked up, and visionary leadership, and they’re going to shoot to the moon over the next few years — starting soon as they release their next FDA trial results in the days and weeks to come, and accelerating by next year as Phase III trials and possible drug approvals get closer to reality.

And no, it’s not the same idea as the “God Switch” ads still being run by Patrick Cox and the Agora folks — that’s a different “become immortal” strategy based on stem cells and they were (and are, and have been for a while) teasing BioTime (BTX). This is a different approach to living “forever.”

Here’s some more from the ad, talking about the huge success this scientist had with his last company:

“In the next 90 days, we’re expecting an unprecedented and shocking announcement from this gentleman’s new ‘start-up’ biotech company…

“It’s a ‘coming out party’ of sorts for this technology.

“And when this news hits the mainstream media, I believe it could become the most talked about technology breakthrough of our lifetimes. And the stock is likely to storm up the charts as a result.”

Here’s how they describe the actual science … and let me just warn you, from here on out I’ll be playing the role of “dumb guy”, the science is out of my sphere of understanding:

“Think of your cells like tiny photocopiers. Even if you have the highest-quality printer in the world, there will be a problem if you make copies of copies of a photograph. The little imperfections add up. Eventually you won’t even recognize the image.

“But, consider if you just used the original every time you wanted a copy. Then you could make perfect replicas for years and years.

“That’s what this company’s technology does.

“Its scientists have found a way to get the ‘original’ make-up of a cell. Its treatments convince the body to use the originals only, and to destroy any damaged ‘replacement’ copies.

“The industry term for this medicine is ‘RNA Interference.’

“Biologically it works like this…

“RNA is a messenger, copying genes from an old cell to a new cell. But what happens when RNA starts transmitting imperfections to the new cells? The answer is what we call aging… when these imperfections add up, and our body starts breaking down.

“But ‘RNA Interference’ stops the RNA from passing along these imperfections. It interferes with these mistakes, so your genes only pass along the blueprint of the original ‘perfect’ cell.

“In other words: All your new replacement cells can be as perfect as the original cells….

“Right now, doctors treat you by working outside in – using either invasive drugs or surgery.

“But using RNA Interference, it’s possible to treat disease by going inside out. That’s because this technology makes it possible to ‘turn off’ harmful genes.

“For example, let’s say one tiny cell in your body begins producing cancerous cells. With RNA interference, doctors can keep the cancer cell from ever reproducing.

“In other words, you can destroy the cancer inside your cells, before it starts.”

And here’s the understatement of the day:

“It’s unlikely you’ll be able to get a shot or pill in the next five to 10 years to get you to age 1,000.”

But they turn that into “still damn good” in the following sentences:

“After all, RNA Interference is still a very new technology…

“At its current level of development, we are perhaps decades away from using it to live a thousand years.

“That said, I am certain this company’s technology will be used to add as many as 60 to 70 additional healthy years to your life.”

Not bad, eh? So which company is this? Clues, please:

“… a small, American-based company, near the campus of MIT.

“This unknown company has unlocked the secrets of RNA. At this very moment, it’s administering these treatments to hundreds of Americans… But those numbers could be on the verge of a dramatic rise. And here’s why…

“We are only months away from an explosive announcement from this biotech company… One that could show up on the front page of every financial newspaper and website across the country.

“This is the start of something bigger than the introduction of flight by the Wright brothers. Even bigger than the birth of personal computers in the 1970s….

“The company I’ve been telling you about was founded by a scientist we’ll call ‘Dr. Allen.’ Dr. Allen is one of our greatest living scientists. In the 90s, he won the Nobel Prize for a different biotechnology, something called gene splicing.

“He’s also a professor at MIT and a member of the prestigious Royal Society of London, which once included Sir Isaac Newton among its members.

“But beyond his many scientific credentials, Dr. Allen is also an incredible businessman. In the late 70s, he founded a company we’ll call ‘Bio-Inc.’

“It was a tiny start-up at the time, but today that company has over $2 billion in annual revenue.

“You’ll be interested to know that Bio-Inc’s stock is up more than 7,547% since Dr. Allen founded it.”

Sounds intriguing, no? Any more little details that we can feed into the Thinkolator? Perhaps just a few …

“… only a $1.3 billion market cap …

“It owns nearly all the patents related to RNA Interference… over 700 granted patents worldwide for RNA Interference. In total, it has over 300 granted or issued patents in the world’s major pharmaceutical markets – the United States, E.U., Japan… No other company comes this close to completely controlling this technology….

…it’s arranging 30 licensing deals with pharmaceutical and biotech companies right now. And even more deals are expected soon….

“Dr. Allen’s latest company has an advisory board made up of scientists from Harvard Medical School, MIT, Howard Hughes Medical Institute, Swiss Federal Institute of Technology and Koch Institute for Integrative Cancer Research. In just three months, this company will announce incredible medical results, which could shoot its stock to the moon.”

OK … so that’s the pitch on the company — how are they going to make us rich? We’re told that there’s a catalyst coming soon — results from one of their trials:

“Dr. Allen’s company is on the verge of announcing incredible results from a Food and Drug Administration study about its top RNA Interference medicine.

“This study, conducted with the Boston University School of Medicine, will be shocking even to most doctors.

“We know. We’ve seen the earlier FDA reports for ourselves.

“The results of this announcement should lead to immediate Phase 3 approval from the Food and Drug Administration. Meaning…

“The first RNA Interference treatment of its kind will soon be commercially available in the U.S.”

“… laser-focused on a treatment for a rare ‘orphan’ disease. By taking this unusual route to get this medicine on the market, the company cut down the final approval time for its RNA medicine to as fast as 12 months.

“Specifically, Dr. Allen’s team is going after a terrible, genetic disease that more than 40,000 people are diagnosed with each year. Most die from it within three years.

“At this point, Dr. Allen’s company is winding down its Phase 2 trials treating this ‘orphan’ disease… based on early reports we’ve seen, after a single dose of this RNA medicine, patients had a 94% reduction of the protein causing this genetic disease. In other words, most of the problems were “turned off” after a single treatment. In addition, side effects were non-existent… we fully expect this treatment will almost certainly pass into final Phase 3 testing in the next three months. And when the company announces this next stage of approval, this event alone could be worth millions in profits.

“The door will be wide open for brand new medicines developed by Dr. Allen and his scientists. In fact, they’re working on five new treatments as we speak….”

So who is being teased by the Oxford Club folks here? Thinkolator sez it’s Alnylam Pharmaceuticals (ALNY), which was actually one of the top teaser touts of 2012 after the folks at Casey Extraordinary Technology teased it back in May of last year at about $10 a share (it went to $18 or so at the end of the year, and recent strength has driven it to $30).

I think you probably all know well that I’m no doctor, and no scientific expert, but Alnylam Pharmaceuticals is a very active developer of early stage drugs that use RNA interference or RNAi technology — they’re not the only ones, there are other competing platforms and strategies that also aim to lasso the “turn off a gene” power of tinkering with RNA, including the one that’s probably a bit more well-known, Isis Pharmaceuticals (ISIS). And yes, ALNY is headquartered in Cambridge, not far from MIT, and the big brain on the board is Nobel-winning RNA-splicer (and MIT faculty member) Dr. Phillip A. Sharp — the A is for Allen, in case you’re wondering where the “Dr. Allen” bit came from.

They are also expecting Phase II data from their lead trial sometime this Summer, that’s the trial for their “orphan drug” to treat TTR Amyloidosis (the drug is called ALN-TTR02 at this point), and they do see this moving into a Phase III pivotal trial by the end of the year (assuming, of course, that good results continue). This is an exceedingly rare and terrible disease with no effective therapies, so the treatment would have to be pretty bad to not at least get the drug a fighting chance. You can see the rest of the pipeline here, the goal of the company is to advance at least five compounds into advanced stage clinical trials by 2015 (they call it their “5 in 15” campaign), which would presumably help to validate their RNAi platform and patents and technology and get other partners on board to work on other diseases.

The company has had a pretty steady drumbeat of positive-sounding announcements during the first half of this year, which has helped to spur the shares higher, and the last note I saw in their quarterly annoucements said they expect their Phase II TTR02 results by the end of June, so that’s awfully dang close to now … along with a “data rich” period of expected information being released about their preclinical and less-advanced products over the next few months. They’ve also been making the rounds of investment conferences recently, so you can check out some of those presentations here if you’re interested in hearing their pitch more directly, or the latest earnings call transcript here. That said, they’ve had plenty of periods of weaker news as well — they had a different Phase II trial fail a bit over a year ago, so these are not guaranteed compounds.

Financially, ALNY’s stock price can really only be justified because it’s a biotech stock that investors believe is creating a platform that will lead to a series of novel drugs inching closer to the market over the next several years. Their revenue is minuscule for a company that has a market cap now of almost $2 billion, and they have a couple hundred million in cash on hand but that’s only because they issued new stock this year to raise cash — they will be using all of that cash and more as their clinical development programs move forward, trials are expensive and they get more expensive as you move along to later stages (though their lead candidate, with a very small number of afflicted patients and orphan status to speed things up, may not cost as much to usher through the process as the average drug). The stock trades on sentiment about their clinical trials, and about speculation about what a real platform for RNAi drugs might mean — which almost means the share price is irrelevant, you can argue that the company is worth $500 million or $1 billion or $5 billion or whatever number in between, but it’s all based on the current drugs, all in early stages except for their lead orphan drug, continuing to show the promise of RNA. Massive returns from here, as have been achieved by a few biotechs that made the leap to becoming real “big pharma” names with real products and profits, are possible, I suppose, but that depends on the science working. And probably on a bit of luck, as well.

Oh, and yes, “Dr. Allen” was involved with one of those previous mega-successes — the stock they tease as “Bio-Inc” is Biogen-Idec (BIIB), and Dr. Sharp was the founder of Biogen. If performance like Biogen’s is the goal — and that would be a lofty goal, indeed — then it’s worth noting that even this clearly spectacular company has had some very weak periods of stock performance, so investors would have had to show either great prescience or great patience to enjoy all of that run. BIIB has been a huge success since 2000, running from $50 to almost $250 in just a couple years, and it was also hugely successful in the 1990s, running from a couple dollars in 1990 to almost $50 in 2000 … but it also had a “lost decade” there in the middle, bouncing from $35 to $70 and back again several times in the 2000s as their lead drugs showed promise and disappointment along the way.

ALNY last had a heyday for investors in the mid-2000s when their first compound were being readied for the clinic, and RNAi and SiRNA and other technologies and techniques to silence genes were just getting investors excited for really the first time. RNAi and the like have been very promising but very challenging develop for at least a decade now — that oft-cited quote that was in the ad that this is “The Greatest Medical Advance Since the Discovery of Antibiotics,” from an article in New Scientist, was published in 2005, when the first clinical trials for RNAi drugs seemed likely … it always takes longer than you think, and the FDA is always extra-worried about brand new treatments or technologies.

From what I can tell in the dumbed-down articles I’ve skimmed, the biggest issue with RNAi is how to delivery it to the right cells, a challenge that is being addressed in many different ways (intravenous, subcutaneous, oral compounds with engineered coatings, etc.).

Anything else I say about the technology or the company’s drugs in development will only further illustrate my ignorance … so I can tell you that the Oxford folks are almost certainly teasing Alnylam, but I don’t know what the news will be from their Phase II trial in the weeks (or days) ahead, how the other compounds in their “five in 15” campaign will develop, what partnered drugs might bring in milestones in the years to come, or how strong their patent portfolio is. This is a very young science still, at least when it comes to actually developing drugs, so I can easily see a successful drug approval in a couple years, if it does indeed come, being hugely important even if this first orphan drug won’t be itself a big enough seller to “make” the company.

If you’ve been an ALNY investor or follow the stock, or just paid more attention in science class than I did, feel free to jump in and let us know what you think of this one.


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190 Comments on "“Biotech Scientists Discover ‘Magic’ Keys to Immortality” (“Dr. Allen’s … RNA Interference Revolution: Your Ticket to Centuries of Health and Wealth”)"

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ectopicbrain
Irregular
37
ectopicbrain
February 10, 2014 8:35 pm

re: PTN: “[AstraZenica] has an agreement with Palatin Technologies (PTN) to develop the use of “Melanocortin 4 Receptors” to treat obesity. Interesting… http://bit.ly/1gj3Iwx

arch1
Irregular
5249
February 11, 2014 5:56 am

Louis thank you. I was unaware of such. PTN sounding better? I think I keep eye on.

David
Guest
0
David
March 24, 2014 11:41 pm

The AstraZenica relationship hit a snag with FDA on the drug that they were working on.

vivian lewis
Guest
0
February 10, 2014 9:24 pm

this site is a mess; people do not stick to the subject but the stuff on social security and living forever is at least fun.
As a Gemini I would like to hear more from Sankaravelyudhan Nandakumar about what the stars have in store for me. too bad he isn’t karmaswamiswami (or is he?)

arch1
Irregular
5249
February 11, 2014 5:41 am

Vivian; Some might argue that chaos has a role in innovation,in any case I enjoy the interplay of intellect evident in many. Perhaps stars best examined in eyes? cheers :-}

arch1
Irregular
5249
February 11, 2014 6:07 am

As to soc. security If I correctly recall, actual Bush/Senate proposal was to allow you to self-direct 1% of with-holding in approved investment vehicle,, T-Bills,gold CDs Gov.bonds etc.etc. with other 99% to continue going into common pot to finance whims of beloved leaders & replaced by ious for grandchildren to pay.

DBMD
Guest
0
DBMD
February 10, 2014 10:10 pm

I’m in for PTN. I once had a female patient present to the ER for anorgasmia as her only complaint, so it must be serious. If you are over a certain wgt you would qualify for bariatric surgery under current insurance plans. If bremelanotide is approved, or has some effect I see no reason why it would not be part of the new health care plans. It will also have an initial price jump as the science sounds novel.

arch1
Irregular
5249
February 11, 2014 6:14 am

For further s.s. info search Galveston social security experience, or see usatoday30.usatoday.com/…/2005-03-15-benefits-reform-g

arch1
Irregular
5249
February 11, 2014 7:56 am

Myron; In re post#32 & your reply I think ‘creation’ indisputable,, question is; created by blind unreasoning chaos or intelligent person/force/alien life-form. Order out of chaos requires what? Many Godphobic I think.

Frenchy
Guest
0
Frenchy
February 11, 2014 8:16 am
Ref #50 Sam, Money Map Press also referred to a another company this week as a “Fountain of Youth”. It is Anika Therapeutics (ANIK). I’m not smart enough to link to it as it was an email so here’s the write up. Perhaps Dr. KSS can decipher this one for us? I apologize in advance for the long write up…. “Job One here at Money Map Press is to identify “Next Big Thing” trends – and then get you out in front of those trends. One of our favorite areas to reconnoiter is the healthcare/biologics arena – and with good… Read more »
David B
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0
February 11, 2014 11:16 pm

HA is nothing new–it’s been in joint inflammation formulas for years now. This sounds like snake oil to me.

Dr. KSS MD PhD
Guest
0
karmaswimswami
February 12, 2014 7:24 am

I can definitely see no reason to be in Anika. It looks overpriced in fact. The yarn about the enchanted Japanese village with its special diet is just so much malarkey as we are always hearing from the diet/supplement/natural crowd. Dietary hyaluronic acid makes not a whit of difference in anything. HA is made by the body. HA products have been around for ages and are made by other companies. To compare Anika with a high-flier that knows how to execute well like Allergan is just crazy.

arch1
Irregular
5249
February 16, 2014 5:57 am

Dr. You have here answered question I had. Thank you.

tanglewood
Irregular
170
February 11, 2014 11:35 am

Hi Shaunus Brousek
Are you aware of this other Gumshoe thread that discusses molecular biology at a high level? Since you have a biotechnical degree, you should be all set. Others have to have the book ‘Molecular Biology for Dummies’ handy!
http://www.stockgumshoe.com/reviews/biotech-supertrader/this-tiny-unknown-biotech-is-about-to-unleash-its-holy-grail-drug/#comment

midorosan
Irregular
46
midorosan
February 12, 2014 12:26 am

I thought death was God’s way of telling you to slow down.

Frank Graham
Guest
0
Frank Graham
February 15, 2014 9:54 am

ALNY is legitimate and will be bad news for undertakers.

Dr. KSS MD PhD
Guest
0
karmaswimswami
February 15, 2014 10:11 am
Frank, legitimate, yes, but also heinously overpriced at present. Alnylam has put the bulk of its effort into commercialization of silencing RNA for transthyretin-mediated amyloidosis. Do you have any idea how rare that is? They are very unlikely to recoup development costs. Moreover, their approach to this elides the fact that this condition is curable by stem cell transplantation. ALNY has yet to demonstrate really long-term efficacy. There is tremendous concern that its approach, the exogenous administration of naked RNA, will stimulate Toll-like receptors and thus lead to autoimmune phenomena. Would you rather have the problem fixed or take shots… Read more »
arch1
Irregular
5249
February 16, 2014 5:42 am

Dr Karma ; have you any thoughts on recent reported generation of stem cells from mature cells using weak acid & further generation of much needed platelets from patients own cells?

Thomas Jefferson
Guest
0
Thomas Jefferson
February 15, 2014 11:02 am

Bernie Sanders…taxing the rich, ..? Were we talking about investments, or did I stumble into a rabbit hole and end up in a Marxist commune reading Das Kapital ?
In my 60’s, I plan on collecting SS for as long as I paid into it, or taking my gold & heading to South America.
Adios.

arch1
Irregular
5249
February 16, 2014 5:44 am

With nod to P.J. O’rourke; after we “Eat the rich” where do we then turn?

peejay
Member
2
peejay
February 15, 2014 4:01 pm

The longer one lives, the more chance one has of dying from something else other than old age.

arch1
Irregular
5249
February 16, 2014 5:36 am

Paul I think that is most sensible statement. As one nearing end of run I think ” no-one gets out of this world alive” agrees with science which seems to show each generation accumulates defect in genes,which does much to explain increase in dis-ease. Too often I think we address symptoms & not cause. To reiterate prior statement in this thread ,do not expect miracles from this company.

peejay
Member
2
peejay
February 16, 2014 6:02 am
Merci beaucoup Frank. The problem is that people only look at the length of life, not the quality. What point would there be to living, say, 1000 years, and be demented for 920 of them? This research is a symptom of the “me” society. “Who care if there’s not enough room or resources for future generations, as long as I can get money now for some supposed fountain of youth?” is what they are really saying. But there is no fountain of youth, only fountains of stupidity. We have a similar mindset with politicians, spending now, with no regard to… Read more »
arch1
Irregular
5249
February 16, 2014 6:19 am

Paul I could not say it better,I still have hope in diety who knows better than we what we need,not what we desire. We do not begin to know capabilities of/ for this earth we call home.

arch1
Irregular
5249
February 16, 2014 6:36 am

To answer possible question I Think diety is Jove, Jehova, Yahweh
Which approximate translation means ” he who causes to become whatsoever he wills”

Myron Martin
Author
202
February 16, 2014 4:17 pm

Frank: You hit the nail on the head, “Too often I think we address symptoms & not cause” and just maybe part of our education on living a healthy lifestyle is learning what doctors don’t tell us! http://abcnews.go.com/Health/Wellness/things-doctors-telling/story?id=16175754

If you follow all the treads offered in the essay you may just become a little more sceptical about medical procedures.

Alan Harris
Guest
0
Alan Harris
February 16, 2014 4:30 pm

Many of us forget that medicine is a business just like any other. Cure for cure sake, money for God sake!

dcinvest
Irregular
22
dcinvest
February 15, 2014 4:23 pm
WOW to all the above. I would like to see a fundamental analysis coupled with management analysis of the few companies suggested that not only have a winning drug potential, but also the know how to take it to level 1), 2), and level 3. Business plans are great but the manipulation of funding and dilution with the usual talk of “investor shareholder value” are usually smoke screens to cover managers and their greed to take profits while we look on with unusual amounts of fear hope and greed. Good way to lose money unless you can figure the way… Read more »
arch1
Irregular
5249
February 16, 2014 5:52 am

David ; I think you are wise to question. I fear many companies exist only to generate wealth for their executives & board of directors. It is much easier to lose money than to gain it. As to greed , as usually used I think everyone greedy in wanting “more”. We all need more during life, that’s why we invest even if only for descendants.

Alan Harris
Guest
0
Alan Harris
February 16, 2014 6:38 am
Myron #4 replies. Not meaning to be at all rude (I have great respect for your musings on mining as you will know….but here comes the ‘but’) but….. your reply encapsulates your general theme of returning to something like a gold standard. As many writers have said, we are running up a debt for future generations that can never be repaid. Thats ‘never’ if currency stays the same value. However, all babies are born into this world without a penny in their pocket. So whether a $ buys them a home or a stick of gum is irrelevant to them… Read more »
arch1
Irregular
5249
February 16, 2014 6:52 am

Alan ; If I may answer, future generation can of course repudiate debt we lay on them,that however does not bode well for those who depend on govt. promises.

Alan Harris
Guest
0
Alan Harris
February 16, 2014 7:13 am

Quite right, it doesnt bode well for those who depend on gov promises……but suggest another option.

arch1
Irregular
5249
February 16, 2014 7:19 am

Alan ;I have no answer, however does not long affect self , it is you who must worry.

huruAguru
Guest
0
huruAguru
June 18, 2015 2:13 pm
The answer to the debt is to plow into the corruption, which, like sucker weeds when cut, will create a wild growth spurt in our fine native soil. Look at overspeculation and corruption in real estate as well as medicaid fraud in Florida. Where is the majority of it occurring? You guessed it: South Florida. We have a lot of crooks in every state, and they reside and thrive in Democrat counties. How about voter fraud in Florida? South Florida. Prescription drug abuse? Yes, yes, yes. The problem with the inner cities isn’t fatherlessness (as conservatives like to say) or… Read more »
Sally G
Guest
0
Sally G
June 19, 2015 8:06 am
However, your thoughts are not backed up by actual statistics: true as it is that holding a job while addicted is very difficult, if not impossible, your remedies target the wrong folks and do nothing to solve addiction, just put the addicted out on the streets where crime is the only option. Look at Portugal, where almost all drugs have been decriminalized: http://bit.ly/1qsbfh8 (“No drug policy, Zobel says, can genuinely prevent people from taking drugs — at least, he is not familiar with any model that works this way. As for Portugal, Zobel says, “This is working. Drug consumption has… Read more »
Myron Martin
Author
202
February 16, 2014 5:00 pm
Alan: Sorry I even got involved in this thread, holds ZERO interest for me, I.E the forum we are on. If you want to address anything to do with your subject I would appreciate your posting on one of my columns where it would be relevant to the themes being addressed. In view of the fact that several bankers have died recently under very mysterious circumstances, and some commentators even stating they believe they were murdered because they “knew too much” in respect to bullion bank manipulations of gold and silver, (I know, reeks of conspiracy theories) the fact remains… Read more »
Alan Harris
Guest
0
Alan Harris
February 16, 2014 5:23 pm

My first thought is ‘Balone’ You are answering questions with questions……still youre the guru and I accept this is the wrong forum so will move to youre next thread. Rgs AH

Alan Harris
Guest
0
Alan Harris
February 16, 2014 5:58 pm

In fact it would clutter up your next musings, so I decided to open it up for discussion here http://www.stockgumshoe.com/?p=17389

bludolphint
Irregular
25
March 5, 2014 10:38 pm
Bloomberg on FRI Feb 28 reads to the main stream what was talked about in columns in quite a few blogs Sprott Embry, Theodore Russell, etc that spoke and continue to speak to the truth that comex would take over a month to settle the shorts on gold. By whom the Cartel of Bullion banks. there are 5 big ones. Talk about a short squeeze coming. I think the Chinese are importing about a year of output of all gold co. each year ,they are going to try and be the reserve currency, perhaps joined by the euro. I totally… Read more »
arch1
Irregular
5249
February 16, 2014 7:13 am

On reflection , please excuse ramblings of old man in re. post 60 . I think that Muslim, Christian ,Israeli find no offense in re. God of Abram, others may, I think agree that forces unseen & unseeable affect our lives. Atheists may dis-agree that is indeed your ‘right’ however I think you don’t have a prayer.

peejay
Member
2
peejay
February 16, 2014 7:29 am

Do you mean the NSA? 😉

arch1
Irregular
5249
February 16, 2014 7:32 am

Paul; love humor

being still
Guest
0
being still
March 1, 2014 5:22 pm
Um, could it be presumed that if people were going to live till 1000 years of age that we could expect the payments to not start for those interested in getting them until they’re AT LEAST 500 years old? Wouldn’t that just totally screw-up the economy in the sense that no younger people could ever get jobs because those that would’ve died and been replaced by younger workers wouldn’t be dying to provide a job for the younger generation? There’s such a cluster screw-up of messing around with the economy with EVERY decision we make going forward as to make… Read more »
Alan Harris
Guest
0
Alan Harris
March 1, 2014 7:53 pm

Old Chinese curse: May you live in interesting times.

Aleisha
Guest
0
Aleisha
March 5, 2014 5:19 am

I like it when people get together and share views.
Great website, keep it up!

Myron Martin
Author
202
March 16, 2014 11:43 am
I find it interesting that the debate between drug (medical) therapies and alternative methods of healing via natural supplements which was about a 50/50 split in the original columns has drastically changed since Dr KSS has (taken over) and become a separate columnist. Now that bio-techology stocks are being touted offering the potential for profits it would seem those who like me are critics of the medical profession have simply disappeared, they no longer comment. Maybe there should be an alternative medicine column that offers people so inclined professional guidance on the best alternative therapies, and I have a nominee… Read more »
Alan Harris
Guest
0
Alan Harris
March 17, 2014 4:46 pm
Come, come now Myron. You are our (much respected) mining specialist. As a pro, you will know that its far better to ask a question than hold out a long held belief set as fact (however formed). Questions elicit answers that educate (all). Imagine if I pronounced ‘They are digging for ice under the pyramids…..trust me, I read it in the National Enquirer….Egypt needs that water source….its gonna be mega.’ Should the team believe me? Surely better that I asked our expert ‘Myron, please tell me, do you think digging for ice under….is a viable idea? Here we have two… Read more »
don_x
Irregular
32
don_x
June 8, 2015 1:13 pm

I think Al Sears’ research and recommendations make sense. I subscribe to his newsletter, but have never bought his promoted products. Worth a look: http://www.alsearsmd.com/
As for vitamins/minerals purchases, I buy from Lifeextension.com and drsinatra.com.

ptilton45
Member
527
June 8, 2015 8:44 pm
Even though I am now a psychiatrist, years ago as a primary care physician, I headed up a holistic medical clinic and have some knowledge of “natural” medical cures. Natural cures are not necessary more effective or safer, but, for the most part cheaper. Good research in this area is sorely lacking and in fact many so called cures have been debunked by studies from the NIH and others, (Gingko Biloba and glucosamine/chondroitin to name a few.) And many herbs, etc can be toxic. And sometimes people believe so strongly in alternative means that they die rather than seek medical… Read more »
omcdac1
Irregular
449
omcdac1
May 7, 2014 2:26 pm

logged in

omcdac1
Irregular
449
omcdac1
May 7, 2014 2:26 pm

“The First Person to Live to Age 1,000 Has Already Been Born…“ is that true ?

Jacinda
Guest
0
Jacinda
August 29, 2015 3:00 am

People lived appr. 1000 years according to the genesis in the bible :). That was before noa’s ark incident occurred. Before the incident, the living condition people lived in was much different than now.

Old Trafford
Guest
0
Old Trafford
May 8, 2014 1:22 pm

can someone decipher this “Magic Calendar” article for me,,,is this real or scam??

http://research.agorafinancial.com/research/video/ftr_magiccal_0414?code=MFTRQ513&n=FTR_magiccal_0414

it smell funny to me

Myron Martin
Author
202
May 8, 2014 4:28 pm

Give me a few months and I might have an answer for you. As an Agora Reserve member (LIFETIME) I just confirmed to-day that I am am the list to receive this new newsletter from Agora, will give you my evaluation after having paper traded it for a few months.

hedy1234
Irregular
419
hedy1234
May 8, 2014 6:35 pm

“””””….there are 36 “magic dates” over the next 12 months that act as little-known price triggers for some of the hottest stocks on Wall Street. These dates refer to when certain drugs are expected to be approved by the FDA. But don’t worry. We’ll analyze and alert you to only the very best of all these stocks and trigger-dates.

The “Magic Calendar” is a critical part of a system that has to do with Agora Financial’s FDA Trader’s first portfo­lio category: PDUFA Booster Shots.”””

Wayne Bertsch
Guest
0
Wayne Bertsch
May 16, 2014 3:30 pm

So, if you believe in this hype, put your money where you belief is – cash in your life insurance policy now, and investit all in ALNY.

Sandra
Guest
0
October 4, 2014 4:41 pm
Fantastic article. Thank you. I was about to do the very same research using the clues in that affiliate marketing piece and your article came up first. Hooray! You did the research for me and approached it intelligently. You gave a report, too. Excellent. You saved me time and money. The responses have all been intelligent, too. You have a new fan!! Yes, it’s me. Your biggest fan as of right now. Thanks again! And thank you to all of those who shared about other stocks that are doing well. I am off to do more research on those now!… Read more »
harpswell
Irregular
32
harpswell
April 8, 2015 10:23 pm
I just sat through a current Oxford Club presentation on ALNY. The presenter did not try very hard to disguise the company (he mentioned that a senior executive was at MIT and had a Nobel for gene splicing, whatever that is) which meant that it took at most five minutes for a reader without access to the Mighty Thinkolater to run down. However, the argument made was that ALNY had locked up “nearly” all of the patents for working with RNA to turn off degraded forms of DNA in new cells (or something). In any case, in those of Dr.… Read more »
Cool Soupy
Guest
0
June 8, 2015 2:22 pm

Back to the original subject. One small problem working another XXXX years to be able to afford to love that long?
Mentally AT THIS TIME it is impossible !!!!!!!!!!!!
I THINK I WILL STAY WITH ENJOYING LIFE AND MY RETIREMENT. (As long as my money holds out.)

alanh
Irregular
3742
June 13, 2015 11:21 am

Please let me know when they invent a drug that will keep me rich till Im 400.

Mac
Guest
0
Mac
June 8, 2015 10:03 pm

Pretty intense stuff today!! Took me several bourbons and a cigar to plow through it all.

Columbo2
Guest
0
Columbo2
June 9, 2015 11:19 am

Not sure what to believe so I just stick with the facts.

Goldie Fego
Guest
0
November 1, 2015 1:04 am

Hi, has anybody got a {real|actual|unbiased{ review of the Forex Megadroid program. Most of the reviews webpages seem to be affiliate links. Cheers

keith allen
Guest
0
keith allen
August 10, 2016 7:32 pm

hi i have a way to make immortality-fresh copy DNA-i am the real inventor of P.E.G. the stuff that made interferon work-i am the true inventor of the cure for heb b and hep C -i gave both to Rockefeller institute in feb 1989

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