It’s a fascinating issue, Michael- perhaps I shouldn’t have used your excellent summary to launch my point of view! ...

Hi, Michael,Your new commentary is excellent; helpful and insightful. You also have a firm grasp of narrative style...

@Doc Gumshoe, please revisit your analysis with these thoughts in mind. If statins were so useful, shouldn't one be loo...

Just my own experience, 20 years ago my Cholesteral level was considered "normal", this level seemed to go up incrementa...

I am 70+ years of age, have never taken a statin (never will), take no drugs, and believe I am quite healthy. I am in b...

I have been taking statins for almost 20 years and I am currently 65. I tried everything to naturally reduce my LDL with...

Re statins: Are those risk numbers relative or absolute?...

I don't recall exactly what I found, but whatever I found when I researched statins led me to stop taking them - and, yo...

Statins have over 300 side effects including type 2 diabetes. Why would an intelligent person choose to take them....

Of course a chatbot would be in favor of statins... A perfect example of the danger of AI. Much like the jab which the b...

Robert Lustig wrote a book recently called Metabolical. If Doc Gumshoe would read it, I think it may change his narrati...

Another great article Doc. Very educational and helpful.Regarding polypills and other attempts to reduce cardiovascul...

Doctors who prescribe statins will tell you it is to "balance" your high and low cholesterol. It need not be high chole...

chocolatejewel on A Non-Statin Pill That Really Lowers Cholesterol, Blood Pressure and Inflammation without Side Effects Would be a Good Investment, Right? / Apr 15, 11:49pm

I feel compelled to add to Dr. KSS's post. I am a retired physician who was treated on and off with statins for high cho...

Thanks to Doc Gumshoe for another valuable, informative post. One point that bears repeating is the effects of statins ...

Well, if you're sticking to the biased data that predominates medical research, then the benefit of statins is only marg...

I think that is part of that the numbers show without a doubt that statins have helped and asking whom it has helped mor...

Answers to comments:To the tribe member who said it was not a “one-size-fits-all” guideline – precisely my point...

I was on statins, mostly maximum dosage for nearly 20 years when my Left Anterior Descending artery (the "widow maker") ...

Doc, Most US Dr.s still recommend statins for patients whose cholesterol exceeds guidelines even if they have had not ...

Statins are dangerous, and often come with many side effects that are worse than the problem they are trying to correct!...

Its all about the money. Re: Original Jupiter Study- In the statin group, there were 141 major cardiovascular events v...

The statins have significant side effects especially in the elderly. I stopped taking Lipitor at age 90. Since then,now...

Bempedoic acid is a significant advance. Why? Because it can be used in patients who can't tolerate statins because of m...

I'll pass. Cholesterol is not the enemy people believe it to be, and the evidence supporting the use of Statins or any c...

Esperion has worked hard to get bempedoic acid & the ezetimibe-bempedoic combo to the point where the FDA green light is...

There are many studies that seem to indicate that persons taking statin drugs appear to have statistically fewer adverse...

I'm 88. My blood pressure measures in the range of 120/65 +/- 5; pulse usually around 60 except mornings ~55. Not diabet...

Vascepa has been tested in conjunction with statins. I think they'd need to do new studies to show its effectiveness alo...

I have no faith in the use of statins in treating cholesterol and many physicians feel the same way. There has always be...

What about the long-term effects of taking statins? If you increase your life span by (say) 10%, by taking statins but ...

Great article Doc! One might think JAMA would be more thorough in vetting 'studies' such as these. Any thoughts on Vas...

The closest thing to a cure is a diet consisting solely of whole plant foods, devoid of all animal products. Since the v...

Another "cover-up" of natural cures? After sitting through most of their video presentation, I opted for their book and ...

$ESPR small position > Esperion Announces Late-Breaking Oral Presentation of Final Results of Phase 3 Long-Term Safety S...

All the plaque and the problems they cause didn't have any effect on my two grandmothers who were born in the late 1890'...

Why does big pharma not look at HDL? Because Statins do not.affect them....

My family typically lives into their 90's (previous 2 generations / both sides). I have high cholesterol, assume they di...

I too agree with these comments. I was put on statins etc. and scheduled for a high-priority triple bypass 18 years ago...

I agree with you 100%. Forty five years ago I was diagnosed with high cholesterol (300 Total) and was put on statins th...

STM, I claim no expertise. I couldn't use statins. I think $ESPR has an important niche. I don't believe that the man...

JohnM on Alternative Health, Supplements and Related / Mar 13, 4:40pm

Author: Roger I guess whether statins provide longevity remains an issue. I had muscle deterioration and problems with...

Lannas, at this moment, you're right. I didn't sell $ESPR. I guess whether statins provide longevity remains in issue....

$ESPR ow Overreaction, price has already moved back up. The value of ESPR is to take place of statins not as add on, IM...

$ESPR, long:- Some thoughts about $ESPR versus "MDCO's inclisiran" as as stated by Citicorp in Pascal's post: In the ...

$ESPRRoger appreciate your comments. And cheers! to 88! Here’s to many more! I too have struggled with muscle p...

Also if you research further you will find that us older people actually need a higher blood pressure to get the require...

$ESPR?"EXPR – if you are in it, stay for the duration of Phase 3. The drug will replace statins – a huge market....

CAPR - he is staying long. It's an exosome play with good Phase 2 data. Will be golden if current trial works.ONCS -...

$ESPR LONGEsperion Therapeutics (ESPR 60.66) target raised to $75 from $20 at Chardan Capital Markets. Firm notes ...

$CWBR $Mitochondria $heart diseasesA newly published report by Johns Hopkins researchers, again, pointed to a Mi...

Welcome to the Gummune Fred & thank you for posting your statins experiences! Long #ZKSS, GREAT Gummune & $ESPR...

Indeed, the risk of becoming type II diabetic from statins is high....unacceptably so. Equally unacceptable is the MD pu...

Two friends that were on statins that became diabetic, a side effect. If he has been on MetFormin for 15 years and takin...

$CWBR Good question for Doc. Will you have a Mitochondria of a ten year old? Did you need statins at ten? Will I once a...

Long CWBRDoes CWBR displace statins and ESPR's solution to lipidemia?...

I am one month short of 88. Quit using statins a few years ago after bad side effects and am using old E Indian medicin...

Statins can result in lower body levels of CoQ10,BUT there is no evidence yet that this is clinically meaningful. It may...

$statins, CoQ-10, heartIf my memory serves me right, Dr. KSS or someone here once said that taking statins can reduc...

FING-B np - First product launch with Fingerprints' touch sensor FPC1028 http://hugin.info/132202/R/2136498/817619.pdf ...

$ESPR (of high relevance)NEJM EDITORIAL "Targeting Inflammation in Coronary Artery Disease" Robert A. Harrington, ...

$NVS - Was surprised I was the first to post about this, but double-checked and saw the above link from rfyjr.I add...

$Statins $ESPR (marketing relevance) - A new study nullified statins' advantage in cancer patients"Examining Bias i...

$ESPR - The trial results here are so good at every checkpoint, it seems criminal for the FDA not to issue some sort of ...

Absolutamente, reina mia! That alirocumab price is deeply discounted, and remember: the PSCK9i's have been SO successful...

it would be fascinating to do a kind of isobolographic waterfall curve here---not trying to confuse people, but for a fi...

JohnM on Alternative Health, Supplements and Related / Aug 3, 12:05pm

Author: hedy1234Comment: $STATINS COQ-10 can help with statin symptoms. ------------------------- Author: Dr. KS...

OK, let's do some critical thinking here. The study on which this all is based appeared in Annals of Internal Medicine h...

Yes, true, it can, especially in ubiquinol form, not ubiquinone. But two caveats: first, no large clinical trial has eve...

$STATINS COQ-10 can help with statin symptoms....

$WSJ article on stopping statins. Thanks for posting. Not sure if father-in-law ever complained of muscle aches, but aft...

jcasteleyn Don't have a WSJ subscription. Father-in-law fell and broke his hip, has off and on dementia-like symptoms (f...

Eyedoc is right. I had a tempestuous dream last night that somehow I was being seen by a physician semi-against my wishe...

Rick, thanks for posting this article. I am astonished that recurrent adverse reactions are this low. I believe that $ES...

$ESPRHere is a summary and opinion from the NEJM journal watch:MEDICAL NEWS | PHYSICIAN'S FIRST WATCH July 25, ...

Hi Dr. KSS. I'd like to add my experiences with Metf0rmin. I've been taking metformin since 2007 at the urging of my ph...

My perennial grievance with statins is that they intensify insulin resistance in both genders, albeit it to a greater de...

And one more from biopharma drive:"This could either be due to lower than expected efficacy, adverse events seen in ...

$MRK Thanks for your comments on the hottest biotech news today. If I understand correctly Doc, to promote anacetrapib, ...

Esperion shares may sputter this morning on new from $MRK that anacetrapib met primary study goals in a CVOT. I hope rea...

JohnM on Alternative Health, Supplements and Related / Jun 21, 10:45pm

12/7/14 Dr. KSS, MD PhD, author of this article, says: December 7, 2014 at 6:58 pmWell, all the statins cause loss...

$ESPR long. Hey Doc - in today's WSJ, "When Cholesterol Drugs Cost $14,000, an Insurance Tug-of-War" Sumathi Reddy write...

Which reminds me: at the last conference call, I did make an error. I alluded to $ESPR having a market cap of $3B, and t...

Do some research on statins and you may find you can save your money on those also. I have and I refuse to take them fro...

I saw no mention of the need to take large doses of C0Q-10 when choosing to take statins. Statins are known to reduce l...

Hi Phil: $RDUS was one Glenn and I worked up together years ago and I felt it would go the distance. I blinked about get...

Dear Doc G -- Thank you for the thoughtful response. I did not mean to imply that you have never differentiated between...

For a discussion of the difference between absolute and relative risk, may I refer you to the Doc Gumshoe piece from 201...

Stock Gumshoe has demonstrated that he has the analytical and investigative skills to uncover marketing scams by individ...

$ABVX and others from LaBiotech - 10 Hot European Biotechs to Observe in 2017 http://labiotech.eu/10-hot-biotechs-europ...

$ESPR - new study results should bode well for Esperion"Statins Increase Diabetes Risk by up to 50% in Older Women" ...

$ESPR Interesting Article: http://blogs.sciencemag.org/pipeline/archives/2017/03/20/what-pcsk9-is-telling-us-about-drug...

$ESPR -Waiting for Dr KSS to weigh in may not be wise. As recently as March 4th, he restated his views which have been ...

$ESPR's annual shareholder meeting will be live and online 17 April 2017 at 8 am.Would be good if 2-3 of this group ...

I nominate that for post of the year!Re genes, a dear friend had very high cholesterol levels from the time when ...

$ESPR long long and increasing position - Thank you Doc for an amazing answer. Your knowledge is deep and you are such a...

This is for mtpoulsen and her query earlier today about $ESPR.I am glad she asked because we've needed to put it, af...

$ESPR long 1/2 position Esperion is up 57% since I established the position early February and the only catalyst I can ...

Allison and GUI, in addition to stock-specific links, there are links to 5 comments about statins on the "KSS Wisdom" ...