Abiding Ambiguity: Achaogen and Arrowhead

By DrKSSMDPhD, April 29, 2015

[Ed. Note: Dr. KSS writes for the Irregulars about medicine and biotech stocks. He choses his own topics, and his words and opinions are his own. He has agreed to our trading restrictions. Enjoy!]

In his smoky baritone, singer Stuart Staples of British midlands musical act Tindersticks is bemoaning how he suspects the woman he loves is seeing someone else: “Hey, I’ve been wondering where you go so late at night?” (performed live here in Glasgow). He continues:

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“The not knowing is easy

And the suspecting, that’s okay

Just don’t tell me for certain

That our love, gone away

It’s gone away.”

Tindersticks may be the most sui generis recording outfit to emerge from the Green and Pleasant Land since The Beatles. About once a year, say on a cold rainy Saturday night, I try to have over someone whose company I cherish, open a bottle of something that Kris Prasad’s exquisite palate would surely endorse, and listen to Tindersticks’ first album (you can listen to all of it here), something that provided the perfect soundtrack  for me for a sun-drenched drive from Lisbon to Seville.

The Not Knowing: It’s not as if biotech investing doesn’t already burden investors with daunting odds, extreme scientific complexity and an innate tendency for valuations to rise or fall capriciously by 50 percent on news. Some situations are truly ambiguous enough to leave you washed up on