AOZ
by SoGiAm | April 16, 2016 5:54 am
#Alzheimer’s_disease , #Obesity , #Zika[1] –
The #Numbers , #$s , #Mystery , #KASH ; #Past #present & #future
Endnotes:
- Zika: https://www.stockgumshoe.com/tag/zika/
Source URL: https://www.stockgumshoe.com/2016/04/microblog-aoz/
#AD – Scientists Explore Ties Between Alzheimer’s And Brain’s Ancient Immune System https://www.npr.org/sections/health-shots/2018/02/18/580475245/scientists-explore-ties-between-alzheimers-and-brains-ancient-immune-system HT ty https://twitter.com/RudyTanzi/status/965275097136279552
#AD – Data Detectives Shift Suspicions in Alzheimer’s from Usual Suspect to Inside Villain http://www.rh.gatech.edu/news/602586/data-detectives-shift-suspicions-alzheimers-usual-suspect-inside-villain
“We made tremendous progress across the spectrum of our Alzheimer’s and diabetes programs this past year, and look forward to continuing this momentum in 2018 as we anticipate reporting topline results in April from Part A of our Phase 3 STEADFAST study of azeliragon in patients with mild Alzheimer’s disease,” said Steve Holcombe, president and CEO of vTv Therapeutics. “Our unique and holistic approach to targeting Alzheimer’s through the receptor for advanced glycation endproducts (RAGE) antagonist addresses three major pathologies believed to contribute to the disease: transport of a-beta to the brain, inflammation and the phosphorylation of tau protein. We’re hopeful that results from the study will be a step toward finding a much-needed therapy for the Alzheimer’s community and the millions of people suffering from this devastating disease.”
ty http://services.corporate-ir.net/SEC.Enhanced/SecCapsule.aspx?c=254081&fid=15484038
Rage Against the Machine – Full Concert – 07/24/99 – Woodstock 99 East Stage (OFFICIAL) https://www.youtube.com/watch?v=F9S-JVKw0mE
During #sleep, your body clears misfolded proteins in the #brain linked with #Alzheimers https://www.nih.gov/news-events/nih-research-matters/how-sleep-clears-brain …
#brainhealth #dementia #neuroscience | TY https://twitter.com/LEAD_Coalition/status/970448555478364160
Stat News: FDA’s updated standards remove an unnecessary barrier to testing #Alzheimer’s drugs https://twitter.com/SGottliebFDA/status/970614340595388416
Very interesting! Seems similar to what David Perlmutter talks about in Brain Maker: Developed countries with high sanitary and sterile environments (low parasitic stress) tend to have highest incidence of #Alzheimer’s as the “gut” (microbiome) is underdeveloped, less robust
https://twitter.com/KevinBCook/status/970397908444106752
TY RT md cn
#AD #mindfulness > Whether living with #dementia/#Alzheimers or #caregiving, #mindfulness could be a helpful path.
https://pbs.twimg.com/media/DXZQ8KqWAAA2Tqq.jpg
ty https://twitter.com/LEAD_Coalition/status/970464913897525248
Dysregulation of the epigenetic landscape of normal aging in Alzheimer’s disease https://www.nature.com/articles/s41593-018-0101-9.epdf?referrer_access_token=mbsQ67rvJOJqwmIUkrMcvNRgN0jAjWel9jnR3ZoTv0OQ7UXgIFLabCzjyGlgA1FRbdbYMLzhpGg1DGz09Rc_KAcgzLXASW2jJOLVtiHbwGmnK_wTLuPCfWMBMdDGhmmjIHmJLq5KQUQSpu7IFv4MJUqVJso4e7Uo1s2aPxGjmpu5QqU4kOgXY_I53q-vO6F_9UWWk6Vozg4OM3k8eLYx9osLrD0PaHc9hrmr63yGPgctUcvTC6ljvNvp1lDumGqdB4LTU4OSNnU26DP1-AfRorgm9clLE_jr-_kPKjwOsrtSrWEynHFSJkDBW9dvBPwuwW32L9fd9aaAKfywElymKNKBb6OKmNGmZ2ZwZG9zdbq7NRE-3k0ok5FV9K2oAnJTDeXebVixl7AodPZm_jqITWbaytrdniDw6UfgPzE8_qFoeqSBtXImYGkBky-O1oKZCGskfaob_QYHtVCAUbq6oTY7K2OKalsZ8kxGLak2h0Fatt2SS6Ihsyk_xyrY7Ksh&tracking_referrer=www.genengnews.com …
Alzheimer’s: Epigenetic Dysregulation May Be Key to Onset
https://www.genengnews.com/gen-news-highlights/alzheimer-s-epigenetic-dysregulation-may-be-key-to-onset/81255557/ ht MD cn TY
Alzheimer’s Amyloid Gets Immune System Trim
https://www.genengnews.com/gen-news-highlights/alzheimer-s-amyloid-gets-immune-system-trim/81255566/? ty md cn
Primate fetal hepatic responses to maternal obesity: epigenetic signalling pathways and lipid accumulation http://onlinelibrary.wiley.com/doi/10.1113/JP275422/abstract thyx Md cn
#AD – #FDA is committed to helping facilitate the development of safe, effective treatments that can address the devastating impact from Alzheimer’s. Our new guidance outlines more modern, efficient pathways for innovation in this area ht ty md cn https://twitter.com/SGottliebFDA/status/972976071590187008
Cures Welcome at FDA https://www.wsj.com/articles/cures-welcome-at-fda-1520803007 Have a great week and beyond ALL! #86Alzheimer’s
Yet More Evidence that Viruses May Cause Alzheimer’s Disease
https://gizmodo.com/yet-more-evidence-that-viruses-may-cause-alzheimers-dis-1827511539 or fungi.
The ‘Big Bang’ of Alzheimer’s Scientists ID genesis of disease, focus efforts on deadly shape-shifting tau protein https://www.utsouthwestern.edu/newsroom/articles/year-2018/genesis-of-disease.html
New development in 3-D super-resolution imaging gives insight on Alzheimer’s disease https://phys.org/news/2018-07-d-super-resolution-imaging-insight-alzheimer.html Best
#AlzheimersDisease > New research may answer why many recent Alzheimer’s clinical trials have failed MEDICAL Rich Haridy Rich Haridy Sept 21st, 2018 https://newatlas.com/alzheimers-amyloid-feedback-fasudil/56442/ #Best2You!
#86AD > Mandelblatt cautioned that her study was still too small to reach any conclusion, but if future studies could replicate the findings, then breast cancer patients might need to be screened for APOE4 before they discuss treatment options: https://www.fiercebiotech.com/research/alzheimer-s-risk-gene-linked-to-post-chemo-cognitive-decline #Best2YOU!
Virtual reality can spot navigation problems in early Alzheimer’s disease
by University of Cambridge
https://medicalxpress.com/news/2019-05-virtual-reality-problems-early-alzheimer.html
#Best2You!
https://assets.boardroom.media/company_logo/ccdd47bd-38a1-4648-a771-398f23d727eb.jpg
$ACW.asx Actinogen Medical > ZanaHES Phase 1 trial read out October 01, 2019
Announcement and Investors Conference Call Slides
https://actinogen.com.au/wp-content/uploads/2019/10/20191001-ASX-1979471-Cognitive-improvement-demonstrated-with-Xanamem.pdf
Investors Conference Call October 2019
https://actinogen.com.au/wp-content/uploads/2019/10/20191001-Actinogen-Medical-XanaHES-results-Conference-Call-Recording.mp3
Xanamem has demonstrated to be an efficacious, safe, brain penetrant, orally available, selective 11β –HSD1 inhibitor with significant pharmacodynamic effects on cortisol > From slide 12
Thank you GoodGriefMike for bringing this company to our awareness!
https://www.stockgumshoe.com/2018/08/alzheimers-disease-2018-the-lay-of-the-land/comment-page-1/#comment-4986855
and
https://www.stockgumshoe.com/2019/10/alzheimers-disease-2019-refresher-and-updates/comment-page-1/#comment-5002449 and thank you Doc Gumshoe!
Best!
$INND Innerscope Hearing Technologies, Inc. https://www.innd.com/
MarkeTrak 10: Hearing Aids in an Era of Disruption and DTC/OTC Devices
Published on July 31, 2019
http://www.hearingreview.com/2019/07/marketrak-10-hearing-aids-era-disruption-dtcotc-devices/
Disclosure:
I have taken a stater position in $INND.
Watch as a 4-year-old boy fighting cancer gets his first hearing aids.
https://twitter.com/GMA/status/1180633770409578496?s=20
Best!
SoGiAm
Nibbled a bit on this as well and has dropped almost 40% in a few days….you still in? Just curious.
Best to you!
$INND Innerscope Hearing Technologies, Inc.
Good to hear from you Wfuiii.
I’ve nibbled again. There will be further dilution, imho.
The Moore family has 58+ million shares and has not sold or traded:
https://twitter.com/inndstock/status/1178429884361662464?s=20
Follow along at @Inndstock, if you wish.
Nibble and patience are the key words at this juncture.
Best!
ACW.asx Actinogen presents latest Xanamem data at AD Conference
https://actinogen.com.au/asx-announcements/
Above is link to pdf link
Best 2 all!