By hipockets, February 12, 2018

This thread was initiated in order to provide a dedicated page for the members interested in following developing events at Aptose Biosciences. All posts made here should be about it. Other comments about biotech should be posted to the latest general purpose biotech thread, which on the date this is being written is https://www.stockgumshoe.com/2018/02/biotech-discussion-continued/ , or to the appropriate stock-specific threads.

As this is being written there are two discussion pages for $ARTH – https://www.stockgumshoe.com/2017/11/microblog-discussion-page-for-arch-therapeutics-arth/ and the original one, now closed to comments, started by AlanH http://www.stockgumshoe.com/2015/08/microblog-discussion-re-arth/ . There is also a special page for $AUPH started by LongOnLife: https://www.stockgumshoe.com/2018/02/microblog-discussion-page-for-aurinia-pharmaceuticals-auph/ .

Comments not suitable for any of the above threads can be posted to the latest clubhouse thread, which was started by AlanH and is now up to Volume 8.

Members posting to any of these threads are urged to follow the etiquette guidelines proposed by AlanH several years ago.

With that bit of housekeeping out of the way, I’m interested in APTO because it’s working on drugs to treat acute myeloid leukemia (AML). My “favorite daughter”, my only child, died from it six years ago just before Christmas and 104 weeks after her daughter, another only child, was born.. At that time, only about 7 % of people diagnosed with it lived longer than 2 years. Diana did not make it that far, although she fought it ferociously by undergoing 2 rounds of chemo and two bone marrow transplants.

Studying AML is just one of Aptose’s programs; the others can be found in the information below.

APTO was introduced to the biotech threads by Dr. KSS on 12/16/16 in the thread THE TWELVE BIOTECHS OF CHRISTMAS: ONE , http://www.stockgumshoe.com/2016/12/the-twelve-biotechs-of-christmas-one/ . His comments, from then till 7/13/17, are documented on the Misc Op tab of the spreadsheet at http://tinyurl.com/KSSDAMAN . I will try to include the later comments soon.

From the company’s website http://aptose.com/ :

Aptose Biosciences employs a mechanism-driven approach to deliver
safer, targeted, first-in-class cancer drugs and diagnostics.

“Aptose Biosciences is a science-driven biotechnology company advancing first-in-class agents to treat life-threatening cancers, such as acute myeloid leukemia (AML), high-risk myelodysplastic syndromes (MDS) and other hematologic malignancies. Based on insights into the genetic and epigenetic profiles of certain cancers and patient populations, Aptose is building a pipeline of novel oncology therapies directed at dysregulated processes and signaling pathways. Aptose ...

This is a discussion topic or guest posting submitted by a Stock Gumshoe reader. The content has not been edited or reviewed by Stock Gumshoe, and any opinions expressed are those of the author alone.

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