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Neurotrope (NTRP) will release its Bryostatin Phase 2b top line data this week (company’s guidance). The primary efficacy endpoint is based on Severe Impairment Battery Scale (SIB). Entry criteria was based on the MMSE score. Secondary efficacy endpoints were based on – Activities of Daily Living (ADL), Neuropsychiatric Inventory (NPI), and Mini-Mental State Exam (MMSE). […]

I’ll be attending the Roth conference this March. If you attend let’s meet up. From this list below, any small companies is a must must meet on a one on one meeting? Company Sector 22nd Century Group Inc (XXII) Healthcare Abeona Therapeutics Inc. (ABEO) Healthcare Abpro Labs (PRIVATE) Healthcare AcelRx Pharmaceuticals, Inc. (ACRX) Healthcare Actinium […]

I’m not sure what happened to the the original text, therefore here comes my second attempt.. I recently made two investments in tiny Alzheimer’s biotech companies: Promis Neurosciences ($PMN.TO) and Neurotrope ($NTRP $NTRPD). I’m interested in making more investment in the real estate located at the intersection of Toxic Oligomers (prions)/Tau/Synapses Regeneration. I explain the […]

Recent Author Comments

On Solving Ray Blanco's "Alzheimer's Disease is Now Completely Treatable" Teaser

ProMIS just published a White Paper. Must read. https://promisneurosciences.com/2016site/wp-content/uploads/2018/01/v.final_.draft_.-White-Paper-LMW-toxic-oligomers.pdf[...]

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On Solving Ray Blanco's "Alzheimer's Disease is Now Completely Treatable" Teaser

Aducanumab is the only drug that has shown meaningful AD efficacy to date. I believe it will be approved (I don't have a position).[...]

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On Solving Ray Blanco's "Alzheimer's Disease is Now Completely Treatable" Teaser

I'm not under an NDA with Promis and I don't have any information that other investors do not have.[...]

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On Solving Ray Blanco's "Alzheimer's Disease is Now Completely Treatable" Teaser

Disclaimer: I'm the largest shareholder in this company. I have no clue what the February 14th headline is. The way to think about PMN310 is a drug similar to Aducanumab that binds to the Toxic Oligomers but doesn't bind the fibril (plaque) which is the[...]

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On MicroCap Conference, Essex House, New York City, October 5, 2017

Also, we can't leave the $BSTG solution rotting for patients sake. I have made it clear to the company and all my bankers, that I want to get involved.[...]

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On MicroCap Conference, Essex House, New York City, October 5, 2017

I met with $HTBX as well yesterday. I bought 100 shares this morning. Planning on oversubscribing.[...]

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On MicroCap Conference, Essex House, New York City, October 5, 2017

$BSTG[...]

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On MicroCap Conference, Essex House, New York City, October 5, 2017

Always at my best when everyone has left the room. Highly risky, but too cheap of an asset ...[...]

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On MicroCap Conference, Essex House, New York City, October 5, 2017

I bought 500,000 shares in the collapse yesterday. I bought another 200,000 shares this morning. I want to be involved with the financing. I'm focusing on the constant, the people will be replaced. In my humble opinion. Michael Bigger[...]

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On Cisco, Chang & Charlie Part 3

Thank you very much for the kind words. The Soundview Research is also an excellent piece: http://s3.amazonaws.com/Published_Research/MRIC_SV_Report_OCT_25_2016.pdf BTW.... I'm working with Soundview Research to combine the 3 pieces (Soundview, Eden Rah[...]

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On Cisco, Chang & Charlie Part 3

If you attend, just ping me on twitter @biggercapital and we'll meetup. The conference is free.[...]

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On Cisco, Chang & Charlie Part 3

Hi Guys! Michael Bigger here. I want to clarify: I believe the stock has a 100 to 1 potential and everyone should do its own due diligence. In my blog post I added the Soundview and the NextEdge Capital pieces on it. On Thursday the company will be present[...]

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On Friday File: "The Penny Stock Index", plus Criteo Crunch (and a small buy)

My take on MRI Interventions, INC. I'm long size. http://biggercapital.squarespace.com/biggercapital-investment/2017/9/6/100-to-1-mri-interventions-inc.html[...]

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On Oncotutorial

And now Saverio just bought another 100,000 shares.[...]

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On Oncotutorial

How Chip Greenblatt implemented it's funding idea from Biostage is nothing short of spectacular. I intend to buy my allocation on the rights offering and then exercise my over-allotment allocation. This is setting up so well.[...]

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On The Conversation: ScyNexis ($SCYX) CFO Eric Francois

Hi all, I participated in the NTRP Private Placement. I wrote a post about it in the Readers' Discussion section: https://www.stockgumshoe.com/2017/04/microblog-momentous-alzheimers-disease-readouts/ I might be wrong, but one thing that is overlook is[...]

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On Microblog: Gold and Silver and Hard Assets after Trump's Inauguration...2017

Griffin, I'm not a commodity guy but I'm making my first investment in Uranium. Western Uranium Private Placement. My partner has been talking to most Uranium companies CEOs in the last 6 months and has even written a 25 pages thesis on the subject. he lov[...]

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On The Rest of the 12 Biotechs of Christmas

1. is erroneous. 1 dose is irrelevant for compassionate use. It was multiple doses.[...]

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On The Rest of the 12 Biotechs of Christmas

The hight short in BIOC might be due to hedging the warrants. I participated in the deal but haven't hedge my warrants and I don't intend to do so but other players are hedging, Because it is about hedging a derivatives, the short # has less meaning in my [...]

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On Microblog: Help Me Identify Alzheimer's MicroCaps Winners

Very cool. Thank you.[...]

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