Michael Jorrin, "Doc Gumshoe"

Author Bio

I have been a medical writer for about 25 years; before that I was a documentary film maker, and some of my films were about medical subjects. I am not a physician, but I have a pretty good scientific background. I wouldn’t dream of recommending any kind of treatment to anyone, and I cannot give medical advice. However, I understand the medical literature and the data and evidence behind it, and I have an inquiring and skeptical turn of mind. I scrutinize and question and, sometimes, challenge the positions of some of the established health-care organizations as well as the marketers of health information. Eternal vigilance is a small price to pay for health. — Michael Jorrin (aka DocGumshoe) Michael Jorrin is a paid contributor to Stock Gumshoe, he has agreed to our trading restrictions but he chooses his own topics and his words and opinions are his own.

Author Archives

I was hoping to keep COVID-19 out of this piece, but new things keep flooding in, and I can’t totally ignore them. However, I’ll save them to the end of the story. They are both “good news,” more or less, and I like to leave you with a bit of cheer, when possible. Sleep and […]

This will be the thirteenth Doc Gumshoe pronouncement on the COVID-19 pandemic. Lucky or unlucky, I have no idea, but let’s get on with it. To the question “Where are we now?” the answer depends enormously on exactly where, geographically, we are. The differences in the new case and fatality rates in among the different […]

What started me down this path was a promotional piece for a new drug that was purported to suppress pain through a novel mechanism that prevented the nerve signal that conveyed to the brain a sensation that would usually be experienced as painful from actually being painful. In other words, while mincing an onion, you […]

Before I launch into the topics of the day, I am going to share with you an opinion piece about the recent CDC guidelines. I find myself in complete concurrence with this piece, which was posted a few weeks ago on MedPage Today, a medical website that is a very helpful source of information for […]

I’m happy to report that despite the huge quantity of COVID-related news items that flood my in-box (as well as all news media), the tsunami has not drowned other health and medicine-related releases. Now, with the pandemic retreating – and, yes, it really is retreating – let’s use this as an opportunity to bring a […]

Aside from the tiny minority of people who can actually say what each of those initials stand for, we can divide the populace into two groups – those who specifically know that CRISPR is a tool used in gene editing and those who know (or figure) that it’s a highly promising but exceedingly complex technique […]

This piece was going to be titled “COVID Continued.” Then I thought, “what a depressing title. Nobody wants to read about the continuation of the pandemic. A much more attractive title would be “COVID Terminated.” That’s the headline we want to see. Or, better, that’s the headline we want to believe. How close are we […]

Many of the comments to these Doc Gumshoe pieces go like this: “What do you know about such-and-such a drug, or about what this or that person (usually a physician) has to say about cancer, or heart disease, or (especially these days) about COVID-19?” My right-off-the-bat response to most of these would usually be “not […]

Believe me, I’ve been looking forward to putting Doc Gumshoe to work on topics other than COVID-19, which is far from being the only disease that affects our health and requires careful attention.   But as the global case numbers have topped 85 million, and global deaths are approaching 2 million, COVID-19 demands to be […]

That title is just to remind you that there’s a whole lot more going on in the health/medical area than COVID-19.   But the pandemic has a very large untidy footprint which is making a mark on a great many aspects of health-care in general. One recent example which could not possibly have escaped my […]

The term “the duration” immediately recalls the Second World War. Nobody had any idea when it would be over, and so discussions of a lot of World War II-related events and conditions prominently featured the phrase “for the duration” – as in great numbers of combat fatalities would continue to be reported for the duration, […]

Thinking about COVID-19 almost gives me a migraine, or at least a heavy and achy sensation in my noggin – perhaps not an actual migraine, thankfully, but threatening and unpleasant all the same.   Happily, thinking about migraines will not give me COVID-19.   But migraines are by no means a topic of no consequence, […]

If there is a single lesson to be learned from the (I hope) valuable information in this piece, it is that health-care recommendations are somewhat fluid and also somewhat temporary.   Attached to every guideline and recommendation and even to every firmly-stated conclusion in every written or spoken utterance about health care and related medical […]

This will surely not be the last time Doc Gumshoe turns his attention to the pandemic that is now imposing misery on many parts of the world.   I need to acknowledge that when what was then generally called the Wuhan virus first came to my attention, I expressed the view that, despite the dire […]

Recent Author Comments

On Responses to Questions and Comments: August 2021

The picture with the booster shots is fairly complex. I’m planning to devote a fair chunk of copy to that subject in my next installment, which I’m working on now (just having returned from my vacation on that small island off the coast of Maine). The [...]

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On Doc Gumshoe's Responses to Comments and Questions

The picture with the booster shots is fairly complex. I'm planning to devote a fair chunk of copy to that subject in my next installment, which I'm working on now (just having returned from my vacation on that small island off the coast of Maine). The[...]

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On Responses to Questions and Comments: August 2021

When you say Rife "cured" 18 cancer patients, you may be engaging in the "post hoc propter hoc" fallacy. He treated the patients, and then they got better? Not sure exactly why. How many patients didn't get better?[...]

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On Responses to Questions and Comments: August 2021

Ivermectin was discussed in detail in my preceding piece, posted on August 2nd. Short answer - no evidence supports its benefit. One caveat - people are taking an ivermectin formulation that is used for deworming cattle under the mistaken impression th[...]

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On Responses to Questions and Comments: August 2021

I received blue light therapy to prevent all the little sunburn spots on my face (that had emerged about 65 years after I had given up being a lifeguard) from turning into cancers. It got rid of all those little precancerous spots - did it also improve m[...]

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On Responses to Questions and Comments: August 2021

I'm keeping an eye on the ARMOR study. They are substituting meglumine for the free form of aramchol. We'll see.[...]

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On COVID-19: Keeping Up With the Current State of the Pandemic

I'm sure you're aware of the recent CDC recommendations -masks to be worn including by the vaccinated in any indoor spaces in parts of the US where transmission is above a certain level. That turns out to be just about everywhere. As far as data, there[...]

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On COVID-19: Keeping Up With the Current State of the Pandemic

America's Frontline Doctors was discussed in some detail in a previous post. I have serious doubts about their position, especially with regard to HCQ.[...]

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On COVID-19: Keeping Up With the Current State of the Pandemic

I don't think there are comprehensive data that differentiate between those four cohorts. Developing immunity via vaccines versus infection with the pathogen follows the same course - antibodies first, followed by longer-lasting cellular immunity via B a[...]

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On COVID-19: Keeping Up With the Current State of the Pandemic

It's on my list of subjects to check into. Thanks.[...]

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On Alzheimer’s in 2021: Plus ça Change, Plus C’est le Même Chose

Thanks very much - I 'll check on Leukine & AD. Appreciate the hint. Good luck with your mother![...]

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On Alzheimer’s in 2021: Plus ça Change, Plus C’est le Même Chose

I'm very, very glad to hear that your husband did so well on Fasudil. It bodes well for the great numbers of AD patients who will be eligible after the Phase 3 trial - if, of course, the results continue to be outstanding. But is there no provision in [...]

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On Alzheimer’s in 2021: Plus ça Change, Plus C’est le Même Chose

Lots of stuff for me to check up . Which I will do! Small addendum - several prestigious medical centers including the Cleveland Clinic have stated that they would not use aducanumab/Aduhelm because they doubt whether it delivers any benefit to AD pati[...]

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On Understanding Pain

Sorry you got bored, Darrell. But prior to my little joke about cyanide ending your pain, I did say that "I definitely did not believe the hype ..."[...]

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On Friday File: Fed Foofaraw, and a Hodgepodge of Real Money Portfolio company updates

Travis, your little burst of steam is superb! Thanks a whole lot![...]

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On Is "The End of Alzheimer's" Going to be "Jeff Bezos' Next Big Thing?"

Denali does have a drug, DNL 151, that penetrates the blood-brain barrier. It targets a gene that can lead to Parkinson's. - not Alzheimer's. Looks to me that if DNL 151 amounts to anything, Biogen will reap a big part of the profits. But if Dena[...]

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On Responses to Questions and Selected News Items

I’ve hugely enjoyed the wide-ranging comments that have come in during the past 24 hours. Gumshoe Nation, it seems to me, is representative of Planet Earth in microcosm. We, in the more developed parts of the world, seem to be emerging from the pande[...]

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On May Miscellany – Some Covid-19, Some Otherwise

Your problems are indeed challenging to the utmost. May your situation improve! However, all the evidence I have seen indicates that aerobic exercise in particular delivers the same benefits to the brain and mind as it does to the body.[...]

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On May Miscellany – Some Covid-19, Some Otherwise

Those vaccines do not make people immortal, but they do very effectively protect us from the most dire effects of the coronavirus - as well as depriving the virus of opportunities to multiply and infect others,[...]

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On May Miscellany – Some Covid-19, Some Otherwise

I don't know anything about Fasudil, but I'll put it on my lookout listl[...]

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