Topic Archives: antisense

[Ed. Note: Dr. KSS writes about medicine and biotech stocks for the Irregulars. He has agreed to our trading rules and he chooses his own topics. His words and opinions are his own. Enjoy!] In June 1962, women working in the dressmaking arm of a certain American textile factory were overcome with fear. Rumors began […]

Last week we started to look into the “Curing Cancer Portfolio” tease from the Casey Research folks, and, as promised, today we’re going to finish up and identify the other three picks for you. He says optimistically. (I’m writing as I research here, so we’ll have to see if all three disrobe for the Thinkolator […]

Comments

  • SoGiAm

    MGEN benefits from nusinerin, kynamro, patisiran, inclisiran - they give investors a way to visualize a path to market f...

  • Dr. KSS MD PhD

    Hi Scott: Welcome to the gummeratti clan. I think we can't say for sure about long-termness of $CAPR as an investment un...

  • Dr. KSS MD PhD

    Not to dabble in the mystical, but it fascinates me again and again how bad karma can be indelible in biotech. Bad karma...

  • Dr. KSS MD PhD

    One person's opinion: I don't think Akcea is going to be a haymaker for $IONS. I don't care what Ionis and acolytes clai...

  • Dr. KSS MD PhD

    This was also covered recently here by linling. I think the likelihood that this approach will meaningfully help ALS and...

  • achandra13

    $ARWR Sorry to hear that Kenny. I bailed out on ARWR last year after Benitec and Antisense debacle. RNAi space seems to ...

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    $IONS Jim Jubak also picked $INCY so not all bad :) Sometimes the importance of a clinical trial extends way beyond t...

  • SoGiAm

    $NEOT - Neothetics Inc http://www.neothetics.com/lipo.html no position Maria Feldman Vice President, Clinical Rese...

  • SoGiAm

    Translation efficiency of mRNAs is increased by antisense oligonucleotides targeting upstream open reading frames http:...

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    Nope - - it didn't work. So here is the long version: When the director of research at Cold Spring Harbor Laboratory ...

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    Interesting article on using antisense technology for treatment of breast cancer, with the promise of being successful i...

  • Dr. KSS MD PhD

    Well, certainly not Intermune and what became of it and its drug pirfenidone. I'm aware of and tracking a small Australi...

  • Dr. KSS MD PhD

    Saturday am biotech tutorial: From time to time, we have mentioned miRNA, which stands for microRNA. It's different f...

  • Dr. KSS, MD PhD

    Hi Don...good and relevant questions. It's hard to know what Sanofi post-Viehbacher will be like. Although he's competen...

  • Dr. KSS, MD PhD

    Someone was asking about Anthera $ANTH. It's one we commented on briefly during the summer of 2014 at which time shares...

  • Dr. KSS, MD PhD

    Sheila: she's by training a pediatric endocrinologist who specialized in treating familial hypercholesterolemia in adole...

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    Antisense ($ATHJF) hasn't been discussed in awhile. I have sent an email to them asking for some additional information ...

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    I apologise for being off topic but cant see where else to ask this 1. Are Benitec and Antisense still being held? 2....

  • Dr. KSS, MD PhD

    Missive for a Thursday morning: Here's a,link to the full text of the NEJM article on new oral agent mongersen (sound...

  • Dr. KSS, MD PhD

    An interesting thought, but for sake of devil's advocacy, keep in mind that the clinical utility of RNAi still hasn't re...

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    $ISIS - moving up this morning on a collaboration with Jansen Biotech (a unit of JNJ) that potentially can bring in upwa...

  • Dr. KSS, MD PhD

    Thanks George. Long in holding and buy in sentiment on the last three of those. Buy in sentiment on blue also, just don'...

  • Dr. KSS, MD PhD

    Thanks for reading and posting. I have been aware of this suit, and am unconcerned by it. Biotech often has us facin...

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    All my AZ biotechs had been losers and hold them no more– Admedus, Antisense, Benitec, QRXPY, Prana. I am much happier...

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    $ATHJF (ASX: ANP) Although I would normally follow (the real) Moses in a heartbeat, I would recommend extreme caution...

  • Dr. KSS, MD PhD

    Those who are interested in RNA silencing (siRNA, RNAi, antisense RNA, ddRNAi) are invited to join us on the biotech thr...

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    Has anyone seen this and/or any particular comments re viability, value blah blah blah??? I admit, it was the term ANTI...

  • Dr. KSS, MD PhD

    $CELG popping nicely on heavy volume today on the basis of study data being presented at at an EU GI meeting today on it...

  • Dr. KSS, MD PhD

    I definitely can't hide that that video unsettles me. Isn't Patrick Cox a teaser letter writer? Is he a paid promoter? ...

  • Dr. KSS, MD PhD

    Good data to be presented tomorrow for a Celgene tie-up. Data is phase 2 for Crohn's disease, and involved use of an ORA...

  • Dr. KSS, MD PhD

    One point I would like to remake about Australian biotech investing is this, and it's one I have made both in public and...

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    Apparently not so favorable announcement by Antisense. Looking to issue more shares at A$0.115 . Offer open to current ...

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    For Dr. KSS re Comment 296 above: Voila! Your description of administrators (or managers) as "conniving troglodytes" ...

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    Here is the text of the Antisense announcement referred to by Jack in Comment 286 above: “Tuesday 23rd September 20...

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    DR.KSS; Antisense with some interesting news has declared a trading halt....

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    Antisense: ATL1103 Phase II Trial - Successful Efficacy Results • Primary efficacy endpoint met with a statistically...

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    Dr. KSS, I thoroughly enjoyed your scholarly and indignantly humorous Antisense posts this evening! You really can write...

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    I had to drop my price down to .155 to sell my remaining Antisense shares on the ASX tonight, but I feel cleaner already...

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    To provide added liquidity, I hold my Antisense shares under ANP on the ASX....

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    Antisense SP climbed from 0.15 to 0.185 in first 30 minutes of ASX trading, but has nosedived back down to 0.16 in the l...

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    So, in other words, Antisense is Nonsense..........

  • Dr. KSS, MD PhD

    I would strongly encourage people, after thinking for themselves, to dump Antisense in the am. It will be downhill strai...

  • Dr. KSS, MD PhD

    The goal of therapy in acromegaly is attainment of a normal IGF-1 level. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12...

  • Dr. KSS, MD PhD

    This is honest-to-goodness caca data from Antisense. People seem not to have noticed what is buried in it. That they ave...

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    I think those that sold Antisense may regret it in the morning. This announcement looks very good to me. Have to watch w...

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    Here is an encouraging news release from ISIS (Benitec's foster parent): CARLSBAD, Calif., Sept. 2, 2014 /PRNewswire/...

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    Still no announcement/news on the ASX where Antisense is based. May have to wait for the markets to open in OZ in about...

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    Dr KSS, As I was reading the article that Glenn provided me about the Antisense's trading halt, the only thoughts that ...

  • Dr. KSS, MD PhD

    I have been making some dispassionate observations, both here and at my twitter feed, for a couple of weeks about Antise...

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    I am not as sanguine that the trading halt for Antisense portends positive news. For one, there has been no upward sp...

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    Posted this on the Oxidation thread as well... “Trading halt on shares of Antisense (ANP / ATHJF). Securities will be...

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    "Trading halt on shares of Antisense (ANP / ATHJF). Securities will be placed in a trading halt session at the request ...

  • om sharma

    The securities of Antisense Therapeutics Limited (the “Company”) will be placed in Trading Halt Session State at t...

  • Dr. KSS, MD PhD

    New study portends failure of Antisense (ATHJF/ANP) agent for MS, which dials down expression of leukocyte trafficking m...

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    Dr. KSS, you mentioned you are no longer a fan of Antisense and believe it will go lower. If they have good news from t...

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    Alan im not sure at all if ANP has got it right this time around... Its not a difficult target, im sure that's why Dr Ks...

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    I would like to see it double very quickly, then it should send the sp north of $0.50 in the near future and set it up f...

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    Looks like Antisense news out . Per relativity this is what I build. They aren't exact as ranges can always expand b...

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    JZ Do you have any thoughts on Antisense? acromegaly trial details tomorrow...

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    Antisense update (per 28 Aug ASX Announcement): Company expects to receive Acromegaly trial results on Friday, and wi...

  • Dr. KSS, MD PhD

    Based on the present intrasector rotation out of small cap biotech and into medium and large cap bio, I predict that reg...

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    Antisense company announcement released last week states that clinical data is expected by the end of August (i.e., with...

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    Anyone know when Antisense data is suppose to come out?...

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    Any thoughts on Antisense?...

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    Thanks for keeping us posted on antisense....

  • Dr. KSS, MD PhD

    As regards $ATHJF Antisense, I still have a long position in it. I am awaiting data, which should be out this week, a...

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    Anybody still interested in Antisense Therapeutics from down under? There has been no trading volume for a few days, at...

  • jer_vic

    ANTISENSE (ANP:ASX, ATHJF:OTD) looking for partners: Links HTML: http://email.typeshape.com/t/r-e-mtthdhy-illlzdr...

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    Sweet day in Biotech land for gummies. Benitec,CLDN,NBY,CTIX,RGDO, tearing it up.Whoops, do not want to leave out my QFO...

  • Dr. KSS, MD PhD

    Matt: it may have bottomed here, based on the chart. When I bought RNN, I got in it for Supinoxin, the inhibitor of an R...

  • Dr. KSS, MD PhD

    Om: I am not previously familiar with this Life Sciences Report entity, but I just think they must somehow be a client o...

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    Lawrence,nice post and nice find.If I might add this also, the last part of the press release by the CEO with this stat...

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    For those invested or interested in Antisense Therapeutics (AUS), following is an excerpt from a press release pertainin...

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    Dr.KSS: While I eagerly wait for you to make the case for Amicus (FOLD), and which I took a position in , I am still al...

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    Doc Kss,thanks for looking at Trevena and explaining the science.You have a great way of explaining the science where we...

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    News from Antinsense: ASX Announcement 23 July 2014 ATL1102 for Stem Cell Mobilisation Trial Results An...

  • Dr. KSS, MD PhD

    These are hard times for RNA therapeutics. Maybe Alan has not been being kind to his ancestors? The bad Sarepta news ...

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    Tom mentioned this email from Antisense Therapeutics yesterday from Susan Turner that I received as well.Curious of why ...

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    Looks Like good news on Antisense. I received this in an email. Antisense Therapeutics Limited (ANP) is pleased to anno...

  • Dr. KSS, MD PhD

    All: I closed out my position in Rexahn (RNN) this morning. Let me explain why. It is always critical to follow these...

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    For those invested in Antisense Therapeutics (ATHJF) a recent inquiry for a update about company sent to me this morning...

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    Antisense Therapuetic looks fully funded into 2015 and looking to partner ATL-1102 and ATL-1103.http://www.theage.com.au...

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    This may what helped move Antisense Therapeutics today.A positive article in the Herald Sun.Have to go to second part of...

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    That's weird as INO was up almost 10% in pre-market as rumors of a buy out put out by Cramer... On the other hand, An...

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    Interesting piece that Antisense Therapuetic ATL/TV1102 trial data for targeting MS was actually presented at World Con...

  • Dr. KSS, MD PhD

    Lou L: about indexing, the thing is, we make profits by percentage gains. Whether the company is a behemoth or 5 guys in...

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    sorry that is Antisense> didn't catch the post in time to correct the spelling...

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    NOt sure if anyone has seen this announcement from Antisnese ASX Announcement 2 June 2014 Non-dilutive Funding ...

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    Bradley, I believe JZStoxx was talking about Antisense Therapeutics (ATHJF) at .50 but not 100% sure, sorry....

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    Thanks for keeping us up to date on Antisense and Saunawave Glenn. Do you happen to know who the drugs that are listed b...

  • Anshuman Chandra

    I had no idea so many companies are working on so many drugs. Are all of them private companies except ISIS? ISIS: ...

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    This article would seem to bode well for Antisense Therapuetic's future with their drugs. http://www.raredr.com/article...

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    JZ, just for clarity I have added your comments from April. I have also being trying to take the heat out of this discus...

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    Nope I have no interest in HEB, thus I wont spend the massive time needed to research the lawsuits.... by the way take a...

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    For those of you in Antisense Therapuetic,a good article on their ATL-1102 drug to treat multiple sclerosis.Good trial ...

  • Dr. KSS, MD PhD

    Thanks Dave for the above. I do sort of declare common cause with analog, I do believe in the tech, the method. Manageme...

  • Dr. KSS, MD PhD

    Not sure if people have paid attention the last couple of night to Jam Crammer......not sure what is smoking. Walter Whi...

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    For those of you invested in Antisense Therapeutic (ATHJF) the latest investor update. http://www.antisense.com.au/wp-c...

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    Put quotes around the search in google if you want both words only. In other words search for "Antisense Therapeutic...

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