Topic Archives: antiviral

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    I am concerned about the vaccine and how things will turn out long term. When I was in Panama 2 years ago I was talking ...

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    What's the source for HCQ on its own not working? Here's a long list of studies https://c19study.com/ many of them using...

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    "THAT"S WHAT I'M TALKING ABOUT" This is how we can win! One drug at a time at 'Warp Speed' 3 or 4 therapeutics then a ...

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    Doc...What say you? The Virology Journal – the official publication of the National Institutes of Health – published...

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    Would you please address this as it has become a very confusing issue and apparently now political. Opinion: Fauci Knew ...

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    It looks like messages are getting truncated... for drug company executives to direct their companies to pursue the n...

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    If Gilead's drug, remdesivir, proves successful in the treatment of the coronavirus, I can't see why the company would n...

  • Michael Jorrin,

    Lysol is a disinfectant, not an antimicrobial or antiviral Yes, it will kill viruses on contact & also bacteria. But...

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    I surprised that the Chinese government didn’t mention Chinese star anise. Its most effective antiviral ingredient is ...

  • Michael Jorrin,

    Thanks - I'll check Inovio. There will keep on being new players, both in the antiviral and vaccine spaces. As for t...

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    There is at least one trial already underway to see if antiviral medication can help with Alzheimer's, given the discove...

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    $$CYDY VANCOUVER, Washington, Feb. 20, 2018 (GLOBE NEWSWIRE) -- CytoDyn Inc. (OTC.QB:CYDY) reports the successful achiev...

  • JohnM

    Michael - for your flu article, look at Rapivab, the only IV flu antiviral approved for use in the ICU. Lots of children...

  • JohnM

    $Casey & ER, your post should be required reading for Gummies AND potential ER docs. I know from friends that this flu h...

  • DrKSSMDPhD

    Zimmy.....yes absolutely, and likely by recruitment of TLR's as well (Toll like receptors, ever sniffing for nucleic aci...

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    $THIS and $THAT $WEED.TO, $POT, $MJ $TRPX np :) Abstract: Cannabinoid receptors type 1 (CB1) and type 2 (CB2) ha...

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    $CWBR $Antiviral $Mitochondria dysfunction Hi, Belgiumchocolate: A couple of recent (2017) medical papers may he...

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    $CWBR $COB.U , FP Hi fellow Gummies, I was doing some DD this weekend and here is just a thought I wanted to share...

  • SoGiAm

    $ABVX - Evotec and ABIVAX enter into strategic collaboration to develop novel antiviral agents https://www.evotec.com/a...

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    $RGLS - of interest is language in the 8-K that expands on the problems associated with the clinical hold on RG- 101 and...

  • DrKSSMDPhD

    Sorry, yes it is ABX-464. Other than parking in the stock, which I have done, I have to admit I don't have a sense of cl...

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    $CYDY abstract Abstract Title: Interim Results of PRO 140 in a Phase 2b/3 Study in Treatment-Experienced HIV-1 Patients...

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    $ABVX Has anyone commented on this alternative explanation for the ABIVAX HIV viral reservoir effect: "The explana...

  • DrKSSMDPhD

    Redsox/Peter: To continue musing about Abivax, let me make what I think is an important point. In the early days of t...

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    $noticker Dr. Julius Youngner, Polio Vaccine Pioneer, Dies at 96 "Dr. Youngner was the last surviving member of the or...

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    $ABVX full link in English: http://www.abivax.com/en/news-events/press-releases/479-first-ever-evidence-of-treatment-in...

  • DrKSSMDPhD

    I'm not coming down on you, but I gotta say I am just shocked that you would seriously wield an "analysis" of ContraVir ...

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    12-Apr-2017:06:07:00, Novan Reports Positive Topline Results with SB208 in Phase 2 TrialClinical Evidence of Antifungal ...

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    I have a small position in Abivax. An article published in Retrovirology, 2015, presented an alternative explanation for...

  • DrKSSMDPhD

    New evidence of an increasingly bulked up, entrained and sophisticated biotech industry in Taiwan, long with the scienti...

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    If you like Nano-particles....there are many places to invest . NanoViricides, Inc. (NNVC) is using them as an antivira...

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    $GILD $RGLS W #HCV #HCC #TumorEnvironment *Hepatocellular Carcinoma Decreases the Chance of Successful Hepatitis C Vi...

  • DrKSSMDPhD

    This article willfully misleads, Alley. First, it's trying to depict its agent as a prodrug of tenofovir and implies Gil...

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    $RGLS On Wednesday the NYT published, "Are New Drugs for Hepatitis C Safe? A Report Raises Concerns: https://www.nyt...

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    A phase 1b of RG-101 was published in The Lancet recently: "Safety, tolerability, and antiviral effect of RG-101 in p...

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    This abstract more than likely moving RGLS of late. Background and aims: MicroRNA (miR)-122 is the most abundant mi...

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    $GILD Very interesting... Here we describe a patient with advanced follicular lymphoma and concurrent hepatitis C vi...

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    Would like to present a company here that has been on a tear the last 5 days and has 2 drugs targeting HEP B and shingle...

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    $ARWR $AMGN #HBV - An interesting article published this morning "Arrowhead: Two Collaborations in One Week" Rece...

  • SoGiAm

    $ARWR np - Arrowhead Pharmaceuticals Doses First Patient with Hepatitis B in Multiple Ascending Dose Portion of Phase 1...

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    'twas me that asked you the question! And after reading your opinion, I shall scratch it off my watch list forthwith. Th...

  • JohnM

    $PTN - I don't believe the conspiracy theory that Feuerstein shorts stocks and then writes about them. But I do think a ...

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    There was a piece on ReachMD some years back when it was on XM satellite about a researcher at LSU who was going out wit...

  • JohnM

    $BCRX BioCryst has an approved antiviral that knocks out swine, bird, Zika and most flus in the ICU. Also approved in Ja...

  • DrKSSMDPhD

    Tough but not mean. My rules wouldn't apply in your case as you're being legitimately rx'd a controlled substance, which...

  • SoGiAm

    $ARWR - Arrowhead Pharmaceuticals Presents Promising ARC-520 Hepatitis B Data at The International Liver Congress(TM) 20...

  • DrKSSMDPhD

    Yes, agree, 18 months is a very long time when the virus in question is a labile RNA virus. Not an eternity, but certain...

  • SoGiAm

    From France, a Phase II HIV Antiviral with Promising Results #ABX464 #Abivax #CGIB: https://t.co/Z6TrnC6Pe5 image: h...

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    A small Australian company Nanosonics (ASX:NAN) has developed infection control/ decontamination procedure for ultrasoun...

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    Thought this may be of interest to some. Stock rose just over 120% today. ContraVir Pharmaceuticals, Inc. (NASDAQ: CTR...

  • DrKSSMDPhD

    Arrowhead's HBV data is out for single doses. Somewhat as expected the antiviral efficacy is not as high as I would've l...

  • SoGiAm

    ARWR- Arrowhead Reports Peak Reduction in HBsAg of Up to 99% (1.9 log) After a Single Dose with Hepatitis B Candidate AR...

  • JohnM

    There is a portion of the virus that is conserved during its mutations. Otherwise, it ceases to be a virus. By targeting...

  • Gui_

    TLOG starting over: The company intends to initiate a combination single ascending dose/multiple ascending dose clin...

  • DrKSSMDPhD

    I tend to doubt we will see MERS action here. First, half of all South Korean cases are traceable to one facility. Next,...

  • Patricia

    Well Cyndy, I think you'd agree that we need both natural healing agents AND modern pharmaceuticals! I think the problem...

  • Dr. KSS, MD, PhD

    Hi Stephen: There just isn't clinical evidence that vitamin D use leads to coronary calcification. It's been looked for...

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    Robert - Re PETX – (Aratana Therapeutics ) Chart looks like it starting to form a “cup and handle” pattern. It ha...

  • DBMD

    Since January 2014, a total of 1107 patients have started antiviral treatment. Among genotype 1 patients, 60% were treat...

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    CMRX - Chimerix This is a nice chart. From 14 to 35 in the last year. Working on an Ebola treatment. Chimerix's ...

  • DrKSSMDPhD

    So they studied a mere 34 patients with mild disease, and this makes it into NEJM? Very dismaying. An Interferon-fr...

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    SA Breaking News (Sunday 5:06 pm): Achillion presents HCV data at The Liver Meeting • 5:06 PM At this week's Annual ...

  • DrKSSMDPhD

    It's a fair question...about $ARWR. I got hold of the abstract on 8 October. Michael Yee of RBC Capital or one of his as...

  • DrKSSMDPhD

    Duncan's surviving son and brother contend in their suit against the Dallas hospital that Duncan received no form of inv...

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    Dr. KSS and fellow gummies - an interesting presentation by the UC San Diego AntiViral Research Center on infectious dis...

  • DrKSSMDPhD

    William...yes, what you are describing is a customary angle on antiviral drug design, A "silent mutation" isn't really s...

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    Doc KSS or anyone who may have stumbled across this; Have you ever heard of or what do you know about REPLICor? htt...

  • DrKSSMDPhD

    Doesn't matter.....this is for the old form of tenofovir: TDF. The newer form, TAF, has better antiviral activity and pe...

  • JohnM

    Thank you, Dr. KSS. I think you are exactly right on. I am holding BioCryst (BCRX), but not for its Ebola antiviral....

  • DrKSSMDPhD

    To Jack Weiss: I am in no way a supporter of milkthistle/silymarin use. It is not that it has not been proven to be of b...

  • DrKSSMDPhD

    Hi Doug: glad you are here and thanks for posting. Stick around. It's hard for me to see NNVC ever going anywhere. It...

  • DrKSSMDPhD

    KennyG: I have taken to completely ignoring Pannobhaso because he gets so very much so very wrong. The Tribetarna trial ...

  • DrKSSMDPhD

    Here's an interesting situation: NovaBay Pharm (NBY) is a $40 million company in California that is developing a novel c...

  • JohnM

    Dr, KSS - RE Marburg and Ebola, BioCryst (BIOC) has an antiviral for most (all?) hemmoraigic fevers in animal trials. No...

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    I believe the truth is somewhere between the medical doctors who belittle alternative or complimentary health care, and ...

  • DrKSSMDPhD

    Diana: to me that is definitely a risk. And while chlorination is reasonably antibacterial, its antifungal and antiviral...

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    HEB's Aferon(R) N shows anti-MERS activity in vitro. http://www.investorvillage.com/smbd.asp?mb=270&mn=232&pt=msg&mid=1...

  • DrKSSMDPhD

    Frank: there are some physician message boards, and just during the weekend, hints are being dropped that Alferon has be...

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    gumshoegabby: I agree; the most successful antiviral therapy is immunizations; the problem is how to help the body find ...

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    FYI: LA JOLLA, Calif., March 5, 2014 /PRNewswire/ -- Regulus Therapeutics Inc. (NASDAQ:RGLS), a biopharmaceutical comp...

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    I have no position but its nice to see the space get recognition. I have the full report but weary of posting. Arr...

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    This is a safety concern with the FDA (and EMEA) as there is no off switch. This is one reason why therapeutic vaccines ...

  • karmaswimswami

    Biocqr: Milkthistle is silymarin ("silly," get it?). I would not be caught dead recommending this nonsense and would ost...

  • karmaswimswami

    It is frankly difficult for me to get interested in NNVC (Nanoviricides). Its agents are sequestrants, partitioners. Vir...

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    I would be curious to hear KSS's take on NNVC... NanoViricides, Inc. (www.nanoviricides.com) is a development stage c...

  • karmaswimswami

    You are quite right George. In the days before DAA's for HCV, the single best and most potent interferon-alfa (consensus...

  • karmaswimswami

    JJ: Thanks for your comment. You are quite right about M. Graham. The specific guy who designed TT-034 with its three sh...

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