Topic Archives: Calimmune

[ed note: Dr. KSS is a paid contributor to Stock Gumshoe who writes about biotech stocks for (and discusses them with) the Irregulars. He chooses his own topics, and his words and opinions are his alone. Enjoy!] Greetings fellow Irregulars!  You’ve all been waiting for it….our first-ever annual ceremony in which we look back on […]

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  • DrKSSMDPhD

    Thanks Scorpio for noting that for sicilia. I would add someone was commenting yesterday that of our recent long ideas, ...

  • DrKSSMDPhD

    Hi forensic: thanks for the insight into the call. It's really helpful when readers impart what they've observed or lear...

  • SoGiAm

    July 19-22 2015, I think Lawrence posted on our calendar some months ago: IAS Vancouver, GILD, Important meeting for G...

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    Tim, Just off the cuff, what do you make of this...?? BTEBY Licensee- Calimmune "...Twelve weeks after human CD34+ H...

  • DrKSSMDPhD

    Sayonara Calimmune http://www.nature.com/nature/journal/vaop/ncurrent/full/nature14264.html...

  • DrKSSMDPhD

    Kenny: TT-034 has never been about curing HCV. It is a way to pose as being in HCV to draw investors while simultaneousl...

  • DrKSSMDPhD

    To Larry McKenna: Thanks for that post about HIV-curing gene therapy and Calimmune and the UC Davis report. I worry t...

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    For Dr. KSS: Re Calimmune HIV clinical study An SA (Panno blog) article published yesterday cites an ostensibly credib...

  • omcdac1

    Researchers are reporting another disappointment for efforts to cure infection with the AIDS virus. Six patients given b...

  • DrKSSMDPhD

    I'll try to keep emotions out of it, but here's why I don't think buying more Benitec shares here is a good idea: (1)...

  • DrKSSMDPhD

    Not not cynicism Frank. Why should people be turned on by a casserole of raspberry-flavored crow served up as news in Si...

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    Interesting article with Calimmune and David Baltimore mentioned. http://www.dddmag.com/articles/2014/11/fighting-hiv-s...

  • DrKSSMDPhD

    Thanks! Have tried to no avail to find abstract. Not sure if this is mechanism for elite controllers. If it is, Calimmun...

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    Exactly right Tim. The companies that they are doing "partnerships" with are as obscure as Beni, or privately owned as ...

  • DrKSSMDPhD

    Well, I can't resist weighing in. I'm not sure which particular Pannobhaso missive contains this (I went over to that si...

  • DrKSSMDPhD

    Important puzzle piece in T.R. Brown and Calimmune study. Conditioning a stem cell recipient (i.e., with busulfan) does ...

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    An article appeared yesterday on the UT-San Diego site re Calimmune. What I found interesting was the fact that it's au...

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    GUYS! Benitec!!!! please tell me you have heard of them? ASX:BLT These guys have the technology that Calimmune in the U...

  • DrKSSMDPhD

    Tim: interesting, but doesn't that really in fact make things all the weirder? On one of Sonic Youth's albums, "Murra...

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    Your last sentence there, Doctor, reminds me...didn't you or some other enlightened blogger recently suggest that Beni's...

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    This article (which was posted on Hot Copper today) doesn't explain the Benitec trades that appear on my screen also thi...

  • DrKSSMDPhD

    Material cribbed from Science today by Jon Cohen about the state of things as far as an HIV cure. Increasingly it appear...

  • DrKSSMDPhD

    Potential mote of dust in the eye of Calimmune: a study presented yesterday at the Melbourne AIDS conference showed that...

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    My guess would be the timeline and Australia's habit of selling the news.... Every piece of good news in this stock as o...

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    Benitec gets an honorable mention from SA's Intrepid Investor. He also writes about BLUE, EPZN, SGMO and REGN. The Be...

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    The statement below was released by Calimmune less than a month ago, it refers to their trial. It says that they are "ex...

  • DrKSSMDPhD

    Dave: I truly wish I knew. Generally licensing agreements have gradations, with milestone payments at various stages of ...

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    Hi Dr KSS : You find out the 133k buyer of RGDO? Benitec has licensing agreement with Calimmune and others using their...

  • omcdac1

    What i think about DdRNAi technology is other company need licence to use ddrani like Calimmune , uniqure and Revivicor ...

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    An article in SF Chronicle about stem cell therapies, and funding from the state of CA's pocketbook - $3bn set aside to ...

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    Some Calimmune news in HIV trials licensing Benitec's technology http://www.businesswire.com/news/home/20140625005962...

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    Benitec announcement concerning Calimmune. http://www.asx.com.au/asx/research/companyInfo.do?by=asxCode&asxCode=BLT...

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    Great part 2, hopefully someday we'll have a part 3 digging in to the details of Benitec's trial data and what it really...

  • omcdac1

    DR KSS, Any idea when Calimmune will start IPO! I am saving $$ for Calimmune Stocks! Thanks...

  • DrKSSMDPhD

    To John Trier: that paper is an intellectualization of the basis for Calimmune's approach to HIV. Geoff Symonds, one of ...

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    I think it is a good idea, but I think it woulda been better a month ago. Yes I know, I'm a master of the obvious, and y...

  • Dr. KSS, MD, PhD

    Here's a closely watched event, and in fact the conference call in the morning may interest some. Blue Bird Bio, which w...

  • DrKSSMDPhD

    To S Hoffman: that's a fine question, and a nuanced one. For the Calimmune trial, patients get harvesting of stem cel...

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    DR. KSS: Thanks again for educating the masses. Assuming relatively healthy subjects, doesn't the ongoing Calimmune ...

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    Here's an interested 5-23 Hot Copper post related (indirectly) to BNIKF: "Prof Anthony Kelleher's team at the Kirby I...

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    John: Apparently the speaker went on standard drugs, the drug-cocktails that are in common use today that cause HIV vir...

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    Herbalix when you go to link to Hot Copper,give the I agree box a chance for a few seconds to get blue outline around bo...

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    Wow, take a look at this video that I found on Hot Copper at Benitec site of a patient that was treated by Calimmune and...

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    Could Calimmune be looking to expand clinical trials to Australia? They are looking for a Clinical Trials Manager there...

  • DrKSSMDPhD

    To Tmills: I meant to reply to that. No, that isn't the reason, I am sure. Calimmune has already done phase I work with ...

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    Here is a reiteration of my post 2 nights ago on the Regado thread (#430)...would welcome all thoughts: ...

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    Any information available on the status/results of the Calimmune trial for HIV? Is it possible that Benni is waiting ...

  • DrKSSMDPhD

    Om: Yes, Blue Bird has been mentioned a few times and I have meant for a while to sift through it. While this is by no m...

  • omcdac1

    One interesting thing about "DAVID BALTIMORE, Ph.D. (Chairman) " from Calimmune In 1975, he shared the Nobel Prize fo...

  • omcdac1

    We are just ready to buy as soon as Calimmune is public :) Waiting ... eagerly .....

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    Oh wow you guys have sure done a lot of research on Calimmune... Tx Thomas for pointing it out to me, gonna enjoy read...

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    Ya Calimmune is an amazing company... HIV gene therapy transffered via stem cells. These guys are ahead of the curve ...

  • omcdac1

    Please go to this and Search for Calimmune Ctrl + F http://www.stockgumshoe.com/reviews/biotech-supertrader/this-tiny-...

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    HI JZ: I am wondering if you have had of your Angel Investors looking at Calimmune. As Dr. KSS has mentioned them they...

  • Subramania Kaushik

    Here is a post by Pannobhaso on Benitec! "For anyone interested in the science, a related, pre-clinical paper by Cali...

  • DrKSSMDPhD

    JZ: Sangamo's is one approach to genetic disease. And a decade ago, one might have argued that its notions versus siRNA ...

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    Doc here are some viral load results posted from a participant posted on the forum board for Calimmune trials. Note star...

  • DrKSSMDPhD

    While I am definitely an investor more than a trader, people really really need to look at the technical formation brewi...

  • Subramania Kaushik

    Seems like Calimmune trials are going well! Check this instablog by Panno! If we have any news published by Calimmune a...

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    To All: our patience will be rewarded soon. Here is the possible participant for cohort 3 in the Calimmune trial posting...

  • DrKSSMDPhD

    Randy; Strong work with Calimmune. A bit of a disingenuous slide by Breton in one answer, and he should have elaborated,...

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    Hi Doc and All: Last nights Oxbridge Biotech Round table event " Is Gene Therapy a risky Buisness" should have been tit...

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    I will be there Nick. I will do my best to Channel the good Dr. with the questions he has provided me with. One of the a...

  • analog68

    Nature Biotechnology | Editorial Is this really the RNAissance? Nature Biotechnology 32,201(2014)doi:10.1038/nbt.28...

  • analog68

    I am going to post this here as it relates to KSS's little jewel. It is copied and pasted from HotCopper as the article...

  • DrKSSMDPhD

    Nature Biotechnology | Editorial Is this really the RNAissance? Nature Biotechnology 32,201(2014)doi:10.1038/nbt.28...

  • DrKSSMDPhD

    Good commentary: Nature Biotechnology | Editorial Is this really the RNAissance? Nature Biotechnology 32,201(201...

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    Hoyland from Hot Copper has posted about Calimmune news. Did a little searching and found the forum thread he was referr...

  • karmaswimswami

    Alan and Randy: Basically Calimmune is trying to use gene silencing to replicate the Berlin patient without stem cell th...

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    To All: I have signed up for the OBR Roundup discussion event at the City of Hope. The topic is the future of gene thera...

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    Hi Karma, from my understanding, the Calimmune trial is a PI/II with the cohorts receiving either Cal-1 alone, or Cal-1 ...

  • karmaswimswami

    Good points Larry. As I see it, Benitec's TT-034 trial is really a study with outcomes on 2 fronts. One question to be a...

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    PS- It was not the Calimmune study that uses Benitek technology. We are still waiting for HIV results for that as I und...

  • karmaswimswami

    To Larry Wright: Thanks for pointing that out. Overall I don't think Sangamo's method is as persuasive as what Benitec's...

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    To Nick Semuta: Loaded question Nick! Who is the closest to having success in a pure ddRNAi trial ? All b...

  • karmaswimswami

    To Lee Baker: I have already speculated here and elsewhere that Gilead may be the Big Cool Friend Benitec needs. As I se...

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    Hi karma, TT-034 was made ready for clinical trials by Pfizer. There is a sufficient amount for the PI/II clinical tria...

  • karmaswimswami

    To Eric Libovitz; Thanks for posting and for providing the link to that paper. It is lovely! Benitec's shRNA methodolog...

  • Subramania Kaushik

    also Benitec licencee, Calimmune, has produced pre-clinical data for its HIV Pl/ll trial http://www.nature.com/article...

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    Doctor K I have been invested in a company AcelRx Pharmacuetical(ACRX) since early stages.Was wondering if you had a op...

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    DR KSS thank you very much for your response in CTSO and Vyralytics.I do not own either and you helped me understand eac...

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    I forgot to also mention that Calimmune have dosed cohort 1 using ddRNAi for HIV as well. This is a therapeutic dose (a...

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    No idea how I stumbled onto this but started reading. Here is what I found: http://californiastemcellreport.blogspot.c...

  • karmaswimswami

    Bill: I also think they are clever. The Zn-finger approach is to suppress T-lymphocyte expression of CCR5, the docking p...

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