Topic Archives: Migraine

When I last took a look at what was happening in the treatment of migraines, I took careful pains to elucidate the differences between migraines and a plain old bad headache – the fact that migraines affect only one side of the head, and a detailed disquisition on the symptoms that many migraineurs (that’s the […]

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    Oh wow, this is such a wealth of information about migraines. I used to think that a migraine is just when my head hurts...

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    Interesting points Dr. Hyland. I'm an episodic migraineur and I do grind my teeth at night. I've gotten a night guard bu...

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    I didn't see mention of changes in air pressure due to weather as a trigger, but that was one that got me every time, ba...

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    Two suggestions. I'm a dentist not a physician. However I've used an NTI devices and had patients use a dental anaesthet...

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    I'd focus on improving GI health first before taking any expensive meds. Healthy guts absorb the right nutrients & b...

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    While usually impressed with Doc Gumshoe analysis, this treatise tends to show him out of his depth. The mention of u...

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    I have followed cannabis investing for years and my conclusion is SCAM!! The scam is the pricing which producers claim ...

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    Could you tell me which CBD you use? I've been taking CBD for two years. I no longer suffer from severe migraine but it'...

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    Thank you for mentioning Aimovig, Ajovy, and Emgality, I never heard for them. I more into natural medicines. You should...

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    i started getting migraines at 40 terrible agonizing , paralyzing ! yes , the worst ones paralyze me on my left side...

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    FYI chronic migraine can change the symptom pattern of one sided pain to bilateral pain. I started experiencing exercis...

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    Michael, regarding the Vascular Hypothesis and imaging studies showing no increase in blood flow that one might expect f...

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    As a parent of a child who suffers from migraines to the extreme - passing out because of the pain... with the greatest ...

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    one of the stocks inthe Global Investing portfolio, Teva of Israel, expects to launch a migraine med based on deuterium ...

  • SoGiAm

    #Private Kardium seeking CE Mark for breakthrough treatment of atrial fibrillation http://www.biotuesdays.com/features/...

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    Avanir Migraine Drug approval just announced - any insight / side effects / etc. that can be offered at this time...

  • Michael Jorrin, "Doc Gumshoe"

    You might check the Doc Gumshoe piece about migraines - "More Than Just A bad Headache: Living With Migraines" - that po...

  • SoGiAm

    #Migraine > https://www.fiercebiotech.com/biotech/lilly-buys-migraine-biotech-colucid-for-960m-and-drug-it-out-licensed...

  • SoGiAm

    #EndPoints : TOP STORIES GlaxoSmithKline’s Hal Barron poaches Genentech’s top cancer drug dealmaker for his new R...

  • SoGiAm

    Blockbuster ambitions: Amgen/Novartis team lines up more promising PhIII erenumab data for some of the toughest migraine...

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    Just wanted to add that while researching for the biotech company for the cancer vaccine I learned that Mangosteen juice...

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    $Ranitidine- I take RX strength dose daily for Barretts and have gotten Migraine type symptoms if I drink even small amo...

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    No ticker Couple of thoughts, if you don't mind... Your symptoms make sense as you are describing them, to a point. An...

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    I remember my neurologist mentioned that I don't fit the profile of someone with a migraine condition. Right-side pain a...

  • DrKSSMDPhD

    I have to say it's rather hard to tie all this together into a unifying process without examining you, particularly in t...

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    $Migraines $Magnesium I have been lucky enough to of never have had a simple headache in my life so far, but I would ...

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    One more thing, how do I know the symptoms were migraine prodrome? I attribute it to my experience with familiar symptom...

  • DrKSSMDPhD

    Are you male or female? Why do you use Flovent? what age are you? What other medications are you on? Have yo...

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    No ticker - I have a medical question that is unrelated to the stock discussion here. Over the last few months I experie...

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    $ AXSM NP Axsome Therapeutics announces AXS-07 for migraine treatment Axsome Therapeutics, Inc. (NASDAQ:AXSM), a...

  • SoGiAm

    $AXSM Axsome Therapeutics Announces AXS-07 for the Treatment of Migraine http://phx.corporate-ir.net/phoenix.zhtml?c=...

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    $AYTU Reverse split 3 out of 4 years. They passed the 2017 reverse split in 2016. Expect more. If you can understand th...

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    I KNOW FOR CERTAIN MAGNESIUM STOPPED MY MIGRAINES... BEEN FREE OF THEM FOR ABOUT 5 YRS NOW... HEADACHE DR. ADVICE SAID T...

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    the problem with drugs to deal with brain plaque to cure Alzheimer's is that we don't know if one causes the other, and ...

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    Migraine drug category getting crowded. https://endpts.com/tevas-cgrp-migraine-drug-aces-phiii-while-rivals-pile-up-at-...

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    Just wanted to share with Gummies a new stock I'm watching: $ZSAN - Zosano Pharma. Couldn't find this one on the Gummie ...

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    $CLCD $LLY $ACOR "The Long-term Effect of Acupuncture for Migraine Prophylaxis A Randomized Clinical Trial” (It w...

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    $CLCD, long Frenchy, I’m a little behind on the threads for the last few days, so I just saw your note on CoLucid. I ...

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    Weird you say that Helen, I am thinking about taking half of my position in CLCD which is up more than 350% in order to ...

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    I thought your comment on COQ10 having negative interactions with statins, beta blockers and anti-depressants quite inte...

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    $AMGN - Implications for $CLCD "Amgen's migraine drug succeeds in late-stage trial" (11/17) Nov 16 (Reuters) - Amg...

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    $CLCD (long) Follow-up on Newby 9/17 press release post: CoLucid Pharmaceuticals, Inc., a biopharmaceutical company ...

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    No position CLCD. I guess I'm luck, I don't know what a migraine feels like. And when I eat ice cream too fast, my thr...

  • DrKSSMDPhD

    Hi lingling: I wanted to reply to your recent post about migraines and lasmiditan from CoLucid. What we're seeing now...

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    $CLCD, $ALDR, #Migraine - $CLCD gained 14% today on raised target price by Piper Jaffray ($36 from $21) based on p...

  • DrKSSMDPhD

    My heartiest congratulations to all CoLucid longs....strong work! I sat this one out NOT because of any doubt but just f...

  • DrKSSMDPhD

    Lannas: it's hard, especially in the nonce, to leave big profits on the table. My honest opinion, FWIW, however, is that...

  • SoGiAm

    $CLCD long - Thanks ZKSS *CoLucid Pharmaceuticals +40% Premarket @$15.01; Co Announced Primary, Secondary Endpoints M...

  • SoGiAm

    $CLCD In - Week of Sept 5, 2016 sharing: http://www.stockgumshoe.com/2016/08/ten-common-biotech-investing-mistakes/comm...

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    For those looking to get in on $CLCD, remember to use limit bids and patience because data due out in two weeks or so. T...

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    We have a few trials due to give results in the coming weeks, so I figured I’d give Commandment #10 a try. First up is...

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    Very nice and useful article Doc, thanks so much. As far as what a SPA means here is a link that explains thoroughly wha...

  • Michael Jorrin (aka Doc Gumshoe)

    Thanks to all for the comments. To Griffin, sorry, but I don't know of any MDs or medical authorities in central Calif...

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    Doc Gumshoe, I suffer from what research I've done is food intolerance. The reason I've decided it is intolerance is t...

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    Dr. KSS, Thank you for the information about the tuning fork. In Jin Shin Jyutsu, a branch of Asian medicine, for a ...

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    To any migraine sufferers out there: For ten years, in my thirties, I had severe migraine headaches twice a month - eup...

  • DrKSSMDPhD

    Many chronic frontal headaches owe to mucus trapping in sinus air cells or pockets under pressure. For example, the baro...

  • DrKSSMDPhD

    The most important thing is not cardiac issues. It's that triptans just are not a very effective class of medicine. They...

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    I should have mentioned above the key point in my opinion is the high percentage of migraine sufferers who have cardio i...

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    Re CLCD , Dr. Lipton presents a strong case for the benefits of Lasmidistan for migraine sufferers with cardiovascular p...

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    CLCD stock price moved up a total of 50% in the 3 days after the meeting from about $6.20 to $9.60. Long CLCD and a m...

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    Regarding Colucid's strong positive movement last week which several asked about above, my take was that it was a result...

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    $CLCD long. Amgen ($AMGN) and Novartis’ ($NVS) migraine drug erenumab has hit the primary endpoint in a Phase II trial...

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    $CLCD "CoLucid Pharmaceuticals Announces Last Patient Randomized in SAMURAI Phase 3 Pivotal Trial of Lasmiditan in Mi...

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    $TRVN In todays press release announcing that Trevena will present at the Jefferies 2016 Healthcare Conference, there...

  • DrKSSMDPhD

    I want to bring readers up to date on CoLucid ($CLCD), a biotech we floated as a long idea last year. CoLucid is phase 3...

  • DrKSSMDPhD

    Thanks a million diplacus: you caught me forgetting some of my own holdings. I promise readers I am not disorganized, bu...

  • SoGiAm

    $CELG - #Celgene highlights key #oncology data at #ASCO16 http://bit.ly/1TZRcCS $TGTX - "Majority of DLBCL responses...

  • JohnM

    I am long $ARLZ. I agree the Canadian drugs are me-too. They are deploying a new sales force this month to bring Fibric...

  • DrKSSMDPhD

    We've not peered in on Alder Bio in a while: it's announcing this am that its mAb against calcitonin gene-related peptid...

  • DrKSSMDPhD

    I may look at entering CLCD here. I have a sneaking feeling they may become a category killer in migraine the way Radius...

  • DrKSSMDPhD

    Yeah, totally nutso. Great company. Great drug....likely to become standard of care for migraine even if not first-line....

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    After this Biotech downturn some that look very enticing and undervalued to me that we follow at these prices with good...

  • DrKSSMDPhD

    To mthunder: Great queries and points. I say bravo to being in both $NK and $CLCD. They are both on my want list.....I h...

  • SoGiAm

    TRVN-Trevena Announces Presentations at PAINWeek(R) 2015 7:00 am ET September 8, 2015 (BusinessWire) Print Trevena, In...

  • SoGiAm

    TRVN-Trevena Appoints Yacoub Habib as Senior Vice President, Business Development and Corporate Planning KING OF PRUS...

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    Amgen's (AMGN) migraine drug report in a crowded field including our beloved CLCD which I hope is tops when it is all sa...

  • SoGiAm

    TRVN Long: Trevena Announces Poster Presentation of Data for Delta Receptor Compound TRV250 at American Headache Society...

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    Thanks Doc for explaing migraine headaches and what Trevena is chasing with its opioid receptor.You are awesome in expla...

  • DrKSSMDPhD

    Glenn: this is in answer to your question from the other thread about Trevena's new delta opioid receptor biased ligand ...

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    Doc Kss, is Trevena (TRVN) chasing the same thing that CLCD is chasing with migraine's?If so I guess you would still con...

  • DrKSSMDPhD

    I am still intensely skeptical: (1) other CGRP acting agents from other companies have failed (2) six months is stil...

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    $ALDR For Migraine sufferers (and investors): Alder Presents Positive Clinical Data for ALD403 at the 17th Congress of...

  • SoGiAm

    TRVN-Trevena, Inc. (NASDAQ: TRVN), a clinical stage pharmaceutical company focused on the discovery and development of b...

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    TRVN corporate update.Long TRVN. Trevena Reports First Quarter 2015 Financial Results and Provides a Corporate Update...

  • DrKSSMDPhD

    No, I am not concerned. I don't want to sound callous, and I know migraine sufferers read here, and I have had a migrain...

  • DrKSSMDPhD

    Mr Paglee....one thing to keep in mind is that CLCD said it was moving from Durham (a brain trust area) to Cambridge (an...

  • DrKSSMDPhD

    Hey Dan: At least 2 other companies have had calcitonin gene related peptide-acting programs for migraine that have fail...

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    Any view on their migraine effort?...

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    CoLucid - Dr. KSS As a former chronic migraine sufferer, I read with great interest your excellent article regarding Co...

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    Thank you for the Special Bulletin on CLCD. I keep telling myself not to buy any more biotech without selling somethin...

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    In response to Doc Gumshoe's article, and to Dr. KSS who says that everything in it and the followup are 100% accurate, ...

  • DrKSSMDPhD

    Avanir was a weird story. I don't think anyone dug their Nuedexta coughsyrup with a college education thing, and huge su...

  • DrKSSMDPhD

    Ben/sogiam, anyone else interested in Alder ($ALDR). OK, I took a pretty thorough look here. For whatever reason Ben ...

  • SoGiAm

    FOR IMMEDIATE RELEASE Data from Phase 2b Clinical Trial of Clazakizumab, an Anti-IL-6 Monoclonal Antibody for the Trea...

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    Alder Biopharmaceuticals has gone from about $10 to $15.72 in a couple weeks. One of their drugs, ALD403, is a monoclon...

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    I've held Pozen for about 10 years, for a net of no gain. Their promise back then was the answer to Migraine headaches. ...

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    Re: # 734 [Frenchy] & # 739 [Jim T.] I believe the great Dr KSS is most assuridly a guy. Back @ 294 on 2-1, His po...

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    Good article on migraine by a neurologist migraine sufferer. Coffee, massage, yoga/meditation, and magnesium are reco...

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