In his tearjerker “Sisters of Mercy,” Leonard Cohen sings, I’ve been where you’re hanging and think I can see how you’re pinned. Although I am less inclined to bash the FDA than many, it has recently let modern medical practice place many patients in an undesirable situation. What if there was a very powerful drug, […]
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Payola from Portola?
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Hi and thanks for posting. I would caution that really none of these metrics applies in this case. This is a wee-cap, sp...
Also long PTLA -For whatever it is worth - I was on warfarin for a number of years after an a-fib incident. Continual mo...
$PTLA longIs Eliquis more effective in preventing strokes or major bleeds in patients who have atrial fibrillation? ...
Helen My apologies for my warfarin question. I did not see yourprophylactic thrombolitic post as I was reading newest po...
In $scyx case,,, could mean This Goose Is Fried. :) But maybe not. Why would a little bit of our good old rat killer ...
Postscript: http://umm.edu/health/medical/altmed/condition/cataracts has some cautions on taking bilberry – not for p...
For those who may not be thrilled over taking warfarin ( rat poison) for a-fib, consider nattokinase. Been studied, and...
Gui....in your situation, warfarin is VERY tricky. You might consider e-mailing me so we can discuss....
@DR. KSS MD PHD Not true. At least for Apixiban rates of major bleeding were significantly lower than warfarin. This...
Hello Doctor, a beautiful saturday to all,I start my first dose of 2.5 mg of Warfarin this evening, my INR being 1.2...
Not true. The present risks of bleeding with warfarin are vastly lower than for inhibitors of factor Xa because warfarin...
The problem from a revenue perspective reversal will require a single dose of Andexxa. Factor Xa inhibitors have lower ...
I think that we have to face the uncomfortable reality that beloranib DOES raise the clotting threshold, and I suspect i...
drbonz I just noticed this reply. I did not intend to imply that the operation is bloody. I was thinking of the aftermat...
The reason those with chronic renal disease are relatively unsafe with warfarin is the result of uremia-induced changes ...
NIHR Dissemination @NIHR_DC 9m9 minutes ago New generation anticoagulants may be safer than #warfarin for people wi...
Joe...I'll be honest: I am peeved at them. This trial should NOT have come to this. Interim data analysis should have wa...
Yesterday in NYT:It is a startling accusation, buried in a footnote in a legal briefing filed recently in federal co...
Although I doubt there's a relation, giving some warfarin by mouth or enoxaparin as a shot would be no problem....
WB I gave up on golden age and now call them the metallic years....where the only gold is in your teeth,silver in your ...
Doesn't have to be either/or. What we may be learning from this is that PWS patients need chronic anti-coagulation, warf...
Not a surprise. One of my major teaching points to medical and pharmacy students is that,IMO, warfarin is the most dange...
DBMD If I am not mistaken anticoagulants do not effect the action of AC5,,a point made, earlier in one of DR KSS postin...
$PTLA Portola The Doc's original article in November Payola for Portola?There are many new blood thinners on the ma...
I have beaten the odds for long term rat poison use [Warfarin} and my thinking is all these products are like wearing a ...
Thanks Jack. The thing is, I hope this is not the reason. It is depicted as "news" and is not, as AC5 has already been s...
Good morning Thank you for interesting reply. I was in bed by the time it came in and my golf this morning having been...
Hi Larry: their non-forthingcomingness is part of the reason I sold my stake, and believe me I feel pain from Regado als...
To Ken Meyer and fisherofmen: Sorry, I got tied up with patients last night and haven't read all the posts yet. Definite...
thanks for the article on blood clotting. I am very interested because my close friend, Kathy Daniel, died of a hemorr...
Just chatting with Michael Fitzhugh of Bioworld Today. Great guy! His report will run tomorrow:By Michael Fitzhugh, ...
People interested in Regado really should go to the link Glenn provided above. You can hear a recording of the presentat...
DR KSS; I can certainly attest the truth of what you say in dealing with Warfarin. I have been on it many years for Afib...
Irreg: that is heinous. So sorry to hear it. I am honestly surprised you did not require arteriography and embolization ...
Thanks Subramania, and thanks for asking.The big problem with heparin is lack of reversibility, as its antidote pro...
To respond to those concerned about the fact that there is no way to undo, "undose," the Benitec therapy for HCV, I migh...
"start low and go slow" doesn't cut it. I couldn't tolerate Warfarin, was put on Bumex. It works, but 1/2 pill makes m...
As a doctor, I think the future of medicine wil be in the genetic research/testing and immmunology based bio-drugs again...